Publicaciones de la RAI

º Dirección Científica

    1. Montes-De-Oca-Fuentes, E. V., Jácome-López, K., Zarco-Mendoza, A., Guerrero, G., Ventura-Gallegos, J. L., Juárez-Méndez, S., Cabrera-Quintero, A. J., Recillas-Targa, F., & Zentella-Dehesa, A. (2024). Differential DNA methylation and CTCF binding between the ESR1 promoter a of MCF-7 and MDA-MB-231 breast cancer cells. Molecular Biology Reports, 51(1). https://doi.org/10.1007/s11033-023-09171-0
    2. López-Méndez, J. A., Ventura-Gallegos, J. L., Camacho-Arroyo, I., Lizano, M., Cabrera-Quintero, A. J., Romero-Córdoba, S. L., Martínez-Vázquez, M., Jacobo-Herrera, N. J., León-Del-Río, A., Paredes-Villa, A. A., Zentella-Dehesa, A."The inhibitory effect of trastuzumab on BT474 triple-positive breast cancer cell viability is reversed by the combination of progesterone and estradiol". Oncology Letters 27.1 (2024): 19.
    3. Díaz-Sánchez, L., Zentella-Dehesa, A., Castro-Torres, V. A., Silva-Jiménez, N., Jacobo-Herrera, N., & Martínez-Vázquez, M. (2023). Evaluations of Anti-Cancer Effects of Combinations of Cisplatin and Tirucallanetype Triterpenes Isolated from Amphipterygium adstringens (Schltdl.). Chemistry & Biodiversity, 20(10). https://doi.org/10.1002/cbdv.202300893
    4. Palma-Flores, C., Cano-Martínez, L. J., Fernández-Valverde, F., Torres-Pérez, I., De Los Santos, S., Hernández-Hernández, J. M., Hernández-Herrera, A., García, S., Canto, P., Zentella-Dehesa, A., & Coral-Vázquez, R. M. (2023). Differential histological features and myogenic protein levels in distinct muscles of d-sarcoglycan null muscular dystrophy mouse model. Journal of Molecular Histology, 54(4), 405-413. https://doi.org/10.1007/s10735-023-10136-7
    5. Esquivel-Chirino, C., Bolaños-Carrillo, M. A., Carmona-Ruiz, D., López-Macay, A., Hernández-Sánchez, F., Montes-Sánchez, D. G., Escuadra-Landeros, M., Gaitán-Cepeda, L. A., Maldonado-Frías, S., Yáñez-Ocampo, B. R., Ventura-Gallegos, J. L., Laparra-Escareño, H., Mejía-Velázquez, C. P., & Zentella-Dehesa, A. (2023). The protective role of cranberries and blueberries in oral cancer. Plants, 12(12), 2330. https://doi.org/10.3390/plants12122330
    6. Cuenca, D., Ventura-Gallegos, J. L., Almeda-Valdés, P., Tusié-Luna, M. T., Reza-Albarrán, A., Ventura-Ayala, L., Ordoñez-Sánchez, M. L., Segura-Kato, Y., Gómez-Pérez, F. J., De Puy Conte, M., Gonzalez, L. R., & Zentella-Dehesa, A. (2023). A novel nonsense mutation in the insulin receptor gene in a patient with HAIR-AN syndrome and endometrial cancer. Molecular Genetics and Metabolism Reports, 35, 100965. https://doi.org/10.1016/j.ymgmr.2023.100965
    7. Navarro-Nateras, L., Diaz-Gonzalez, J., Aguas-Chantes, D., Coria-Oriundo, L. L., Battaglini, F., Ventura-Gallegos, J. L., Zentella-Dehesa, A., Oza, G., Arriaga, L., & Casanova-Moreno, J. R. (2023). Development of a Redox-Polymer-Based electrochemical glucose biosensor suitable for integration in microfluidic 3D cell culture systems. Biosensors, 13(6), 582. https://doi.org/10.3390/bios13060582
    8. Laparra-Escareño, H., Ortega-Gómez, A., Zentella-Dehesa, A., Manzo-Merino, J., Vergara-Ascencio, C. A., Del Carmen Antuñano-Blanco, M., Lopez-Santacruz, J. R., Montalvo-Javé, E. E., Anaya-Ayala, J. E., Lozano-Corona, R., & Hinojosa, C. A. (2023). The effect of cilostazol on the platelet-derived growth factor-beta/beta isoform reduction on venous hyperplasia in an experimental balloon-induced injury model. Vascular, 170853812311621. https://doi.org/10.1177/17085381231162160

º Bioinformática, Bioestadística y Biología computacional

    1. Neri-Rosario D, Martínez-López YE, Esquivel-Hernández DA, Sánchez-Castañeda JP, Padron-Manrique C, Vázquez-Jiménez A, Giron-Villalobos D, Resendis-Antonio O. Dysbiosis signatures of gut microbiota and the progression of type 2 diabetes: a machine learning approach in a Mexican cohort. Front Endocrinol (Lausanne). 2023 Jun 27;14:1170459. doi: 10.3389/fendo.2023.1170459. PMID: 37441494; PMCID: PMC10333697.
    2. Cristian Padron-Manrique, Aarón Vázquez-Jiménez, Diego Armando Esquivel-Hernandez, Yoscelina Estrella Martinez Lopez, Daniel Neri-Rosario, Jean Paul Sánchez-Castañeda, David Giron-Villalobos, Osbaldo Resendis-Antonio. mb-PHENIX: diffusion and supervised uniform manifold approximation for denoizing microbiota data, Bioinformatics, Volume 39, Issue 12, December 2023, btad706, https://doi.org/10.1093/bioinformatics/btad706
    3. Rodolfo Guardado-Mendoza, Yoscelina Estrella Martínez-López, Daniel Neri-Rosario, Diego A Esquivel-Hernández, Cristian Padrón-Manrique, Aarón Vázquez-Jiménez, Jean Paul Sánchez-Castañeda, David Giron-Villalobos, Cristian Mendoza-Ortiz, Maria de Lourdes Reyes-Escogido, Osbaldo Resendis-Antonio, Maria Lola Evia-Viscarra, Alberto Aguilar-Garcia. Gut microbiota in subjects with prediabetes has a low mediating effect on the hypoglycemic outcome of linagliptin/metformin and metformin., 09 November 2023, available at Research Square. https://doi.org/10.21203/rs.3.rs-3378211/v1
    4. Ugo Avila-Ponce de León, Aarón Vazquez-Jimenez, Alejandra Cervera, Galilea Resendis-González, Daniel Neri-Rosario, Osbaldo Resendis-Antonio. (2023). Machine Learning and COVID-19: Lessons from SARS-CoV-2. Springer International Publishing (pp.311-335) https://doi.org/10.1007/978-3-031-28012-2_17
    5. Ugo Avila-Ponce de León, Aarón Vázquez-Jiménez, Pablo Padilla-Longoria, Osbaldo Resendis-Antonio. (2023). Uncoding the interdependency of tumor microenvironment and macrophage polarization: insights from a continuous network approach. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1150890
    6. Diego A Esquivel-Hernández, Yoscelina Estrella Martínez-López, Jean Paul Sánchez-Castañeda, Daniel Neri-Rosario, Cristian Padrón-Manrique, David Giron-Villalobos, Cristian Mendoza-Ortíz, Osbaldo Resendis-Antonio. (2023). A network perspective on the ecology of gut microbiota and progression of type 2 diabetes: Linkages to keystone taxa in a Mexican cohort. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1128767
    7. Romo-Rodríguez, R., Anda, K. G., López-Blanco, J. A., Zamora-Herrera, G., Cortés-Hernández, P., Santos-López, G., Márquez-Domínguez, L., Vilchis-Ordoñez, A., Ramírez-Ramírez, D., Balandrán, J. C., Parra-Ortega, I., Reséndis-Antonio, O., Domínguez-Ramírez, L., López-Macías, C., Bonifaz, L. C., Arriaga-Pizano, L., Cérbulo-Vázquez, A., Ferat-Osorio, E., Chávez-González, A., Pelayo, R. (2023). Chronic comorbidities in middle aged patients contribute to ineffective emergency hematopoiesis in COVID-19 fatal outcomes. Archives of Medical Research, 54(3), 197-210. https://doi.org/10.1016/j.arcmed.2023.03.003
    8. Torres-Flores, U., Díaz-Espinosa, F., López-Santaella, T., Rebollar-Vega, R., Vázquez-Jiménez, A., Taylor, I., Ortíz, R., Echeverría, O. M., Vázquez-Nin, G. H., Gutiérrez-Ruíz, M., De La Rosa-Velázquez, I. A., Reséndis-Antonio, O., & Hernández-Hernández, A. (2023). Spermiogenesis alterations in the absence of CTCF revealed by single cell RNA sequencing. Frontiers in Cell and Developmental Biology, 11. https://doi.org/10.3389/fcell.2023.1119514
    9. Guizar-Heredia, R., Noriega, L. G., Rivera, A. L., Reséndis-Antonio, O., Guevara-Cruz, M., Torres, N., & Tovar, A. R. (2023). A New Approach to Personalized Nutrition: Postprandial Glycemic Response and its Relationship to Gut Microbiota. Archives of Medical Research, 54(3), 176-188. https://doi.org/10.1016/j.arcmed.2023.02.007
    10. Martínez-López YE, Esquivel-Hernández DA, Sánchez-Castañeda JP, Neri-Rosario D, Guardado-Mendoza R, Resendis-Antonio O. Type 2 diabetes, gut microbiome, and systems biology: A novel perspective for a new era. Gut Microbes. 2022 Jan-Dec;14(1):2111952.
    11. De León, U. A., Vázquez-Jiménez, A., Matadamas-Guzmán, M., & Reséndis-Antonio, O. (2022). Boolean modeling reveals that cyclic attractors in macrophage polarization serve as reservoirs of states to balance external perturbations from the tumor microenvironment. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1012730
    12. De León, U. A., & Reséndis-Antonio, O. (2022). Macrophage Boolean networks in the time of SARS-CoV-2. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.997434
    13. Cristian Padron-Manrique, Aarón Vázquez-Jiménez, Diego Armando Esquivel-Hernandez, Yoscelina Estrella Martinez Lopez, Daniel Neri-Rosario, Jean Paul Sánchez-Castañeda, David Giron-Villalobos, Osbaldo Resendis-Antonio. (2022) Diffusion on PCA-UMAP manifold captures a well-balance of local, global, and continuum structure to denoise single-cell RNA sequencing data. bioRxiv. 2022.06. 09.495525. https://doi.org/10.1101/2022.06.09.495525
    14. Guerrero-Escalera, D., Alarcón-Sánchez, B. R., Arellanes-Robledo, J., Cruz-Rangel, A., Del Pozo-Yauner, L., De Sánchez, V. C., Reséndis-Antonio, O., Villa-Treviño, S., Torres-Mena, J. E., & Pérez-Carreón, J. I. (2022). Comparative subcellular localization of NRF2 and KEAP1 during the hepatocellular carcinoma development in vivo. Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, 1869(5), 119222. https://doi.org/10.1016/j.bbamcr.2022.119222
    15. Barajas-Martínez A, Mehta R, Ibarra-Coronado E, Fossion R, Martínez Garcés VJ, Arellano MR, González Alvarez IA, Bautista YVM, Bello-Chavolla OY, Pedraza NR, Encinas BR, Carrión CIP, Ávila MIJ, Valladares-García JC, Vanegas-Cedillo PE, Juárez DH, Vargas-Vázquez A, Antonio-Villa NE, Almeda-Valdes P, Resendis-Antonio O, Hiriart M, Frank A, Aguilar-Salinas CA, Rivera AL. Physiological Network Is Disrupted in Severe COVID-19. Front Physiol. 2022 Mar 10;13:848172.
    16. Vázquez-Jiménez A, Avila-Ponce De León UE, Matadamas-Guzman M, Muciño-Olmos EA, Martínez-López YE, Escobedo-Tapia T, Resendis-Antonio O. On Deep Landscape Exploration of COVID-19 Patients Cells and Severity Markers. Front Immunol. 2021 Sep 16;12:705646.
    17. Avila-Ponce de León U, Vázquez-Jiménez A, Matadamas-Guzman M, Pelayo R, Resendis-Antonio O. Transcriptional and Microenvironmental Landscape of Macrophage Transition in Cancer: A Boolean Analysis. Front Immunol. 2021;12:642842.
    18. Diener C, Reyes-Escogido ML, Jimenez-Ceja LM, Matus M, Gomez-Navarro CM, Chu ND, Zhong V, Tejero ME, Alm E, Resendis-Antonio O, Guardado-Mendoza R. Progressive Shifts in the Gut Microbiome Reflect Prediabetes and Diabetes Development in a Treatment-Naive Mexican Cohort. Front Endocrinol (Lausanne). 2021, 11:602326.
    19. Vázquez-Jiménez, A.; Resendis-Antonio, O. (2021). Stochastic Analysis of the RT-PCR Process in Single-Cell RNA-Seq. Mathematics, 9, 2515.
    20. Martínez-Greene JA, Hernández-Ortega K, Quiroz-Baez R, Resendis-Antonio O, Pichardo-Casas I, Sinclair DA, Budnik B, Hidalgo-Miranda A, Uribe-Querol E, Ramos-Godínez MDP, Martínez-Martínez E. Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. J Extracell Vesicles. 2021, 10(6):e12087.
    21. Barajas-Martínez A, Ibarra-Coronado E, Fossion R, Toledo-Roy JC, Martínez-Garcés V, López-Rivera JA, Tello-Santoyo G, Lavin Rusland D., Gómez JL , Stephens CR., Aguilar-Salinas CA., Estañol B, Torres N, Tovar Armando R., Resendis-Antonio O, Hiriart M, Frank A, Rivera AL. Sex Differences in the Physiological Network o Healthy Young Subjects. Frontiers Physiology (2021) 12, 608.
    22. Muciño-Olmos EA, Vázquez-Jiménez A, Avila-Ponce de León U, Matadamas- Guzman M, Maldonado V, López-Santaella T, Hernández-Hernández A, Resendis-Antonio O. Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq. Sci Rep. 2020, 10(1):12728.
    23. Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, Feist AM, Fengos G, Fleming RMT, García-Jiménez B, Hatzimanikatis V, van Helvoirt W, Henry CS, Hermjakob H, Herrgård MJ, Kaafarani A, Kim HU, King Z, Klamt S, Klipp E, Koehorst JJ, König M, Lakshmanan M, Lee DY, Lee SY, Lee S, Lewis NE, Liu F, Ma H, Machado D, Mahadevan R, Maia P, Mardinoglu A, Medlock GL, Monk JM, Nielsen J, Nielsen LK, Nogales J, Nookaew I, Palsson BO, Papin JA, Patil KR, Poolman M, Price ND, Resendis-Antonio O, Richelle A, Rocha I, Sánchez BJ, Schaap PJ, Malik Sheriff RS, Shoaie S, Sonnenschein N, Teusink B, Vilaça P, Vik JO, Wodke JAH, Xavier JC, Yuan Q, Zakhartsev M, Zhang C. MEMOTE for standardized genome-scale metabolic model testing. Nat Biotechnol. 2020, 38(3):272-276.
    24. Matadamas-Guzman M, Zazueta C, Rojas E, Resendis-Antonio O. Analysis of Epithelial-Mesenchymal Transition Metabolism Identifies Possible Cancer Biomarkers Useful in Diverse Genetic Backgrounds. Front Oncol. 2020, 10:1309.
    25. Diener C, Gibbons SM, Resendis-Antonio O. MICOM: Metagenome-Scale Modeling To Infer Metabolic Interactions in the Gut Microbiota. mSystems. 2020, 5(1):e00606-19.
    26. Banzhaf M, Resendis-Antonio O, Zepeda-Mendoza ML. Uncovering the Dynamic Mechanisms of the Pseudomonas Aeruginosa Quorum Sensing and Virulence Networks Using Boolean Modelling. IEEE Trans Nanobioscience. 2020, 19(3):394- 402.
    27. Graciela Ruiz, Heriberto A. Valencia-González, Delia Pérez-Montiel, Felipe Muñoz, Rodolfo Ocadiz-Delgado, Jorge Fernández-Retana, Carlos Pérez-Plasencia, Osbaldo Reséndis-Antonio, Patricio Gariglio, and Alejandro García-Carrancá. (2019). Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line. Stem Cells International, eCollection 2019, 2019. DOI: 10.1155/2019/7683817
    28. Vanessa L Hale, Patricio Jeraldo, Jun Chen, Michael Mundy, Janet Yao, Sambhawa Priya, Gary Keeney, Kelly Lyke, Jason Ridlon, Bryan A White, Amy J French, Stephen Thibodeau, Christian Diener, Osbaldo Resendis-Antonio, Jaime Gransee, Tumpa Dutta, Xuan-Mai T Petterson, Ran Blekhman, Lisa Boardman, David Larson, Heidi Nelson & Nicholas Chia. (2018). Distinct Microbes, Metabolites, and Ecologies Define the Microbiome in Deficient and Proficient Mismatch Repair Colorectal Cancers. Genome Medicine, 10:78.
    29. Vanessa L. Hale, Patricio Jeraldo, Michael Mundy, Janet Yao, Gary Keeney, Nancy Scot,E. Heidi Cheek, Jennifer Davidson, Megan Green, Christine Martinez, Johm Lehman, Chandra Pettry, Erika Reed, Kelly Like, Bryan A White, Christian Diener, iOsbaldo Resendis-Antonio, Jaime Granseen, Tumpa Datta, Xuan-Mai Petterson, Lisa Boardman, David Larson, Heidi Nelson & Nicholas Chia. (2018). Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer. Methods. 149, 59-68
    30. Itzel López-Rosas, César López-Camarillo, Yarely M Salinas-Vera, Olga N Hérnandez-de la Cruz, Carlos Palma-Flores, Bibiana Chávez-Munguía, Osbaldo Resendis-Antonio, Nancy Guillen, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Esther Ramírez-Moreno, Laurence A Marchat. (2018). Entamoeba histolytica up-regulates microRNA-643 to promote apoptosis by targeting XIAP in human epithelial colon cells. Frontiers in Cellular and Infection Microbiology, 8:437.
    31. Cecilio Valadez-Cano, Roberto Olivares-Hernández, Osbaldo Resendis-Antonio, Alexander DeLuna and Luis Delaye. (2017), Natural selection drove metabolic specialization of the chromatophore in Paulinella chromatophora. BMC Evolutionary Biology, 17: 99.
    32. Nora A. Gutierrez-Najera, Osbaldo Resendis-Antonio and Humberto Nicolini. (2017), Gestaltomics: Systems Biology schemes for the study of neuropsychiatric diseases. Front. in Physiol., 8: 286.
    33. C Diener, Felipe Muñoz, S Encarnacion and O. Resendis-Antonio. (2016). The space of enzyme regulation in HeLa cells can be inferred from its intracellular metabolome. Scientific Report, 6: 28415-28423.
    34. Mahdi Jalili, Ali Salehzadeh-Yazdi, Shailendra Gupta, Olaf Wolkenhauer, Marjan Yaghmaie, Osbaldo Resendis-Antonio, Kamran Alimoghaddam, (2016). Evolution of centrality measurements for the detection of essential proteins in biological networks. Frontiers in Physiology, 7, 375-378.
    35. Contreras Alejandra V, Cocom-Chan Benjamin, Hernandez-Montes Georgina, Portillo-Bobadilla Tobias, Resendis-Antonio Osbaldo. (2016). Host-microbiome interaction and cancer: potential application in precision medicine. Frontiers in Physiology 7:606.
    36. Resendis-Antonio O, Carolina Gonzalez Torres, Gustavo Jaime Muñoz, Claudia Erika Hernandez Patiño et al. (2015). Modeling metabolism: A window toward a comprehensive interpretation of networks in cancer. Seminars in Cancer Biology. 2015 Febrero 30;79:87.
  1. Torres-Ruiz, J., Rull-Gabayet, M., Mejía-Domínguez, N.R., Carrillo-Vázquez, D.A., Reyes-Islas, J.A., Cassiano-Quezada, F., Cuellar-Rodríguez, J., Sierra-Madero, J., Marquéz-Sánchez, J.M., Serrano-García, J.S., González, A.E., Juárez-Vega, G., Tapia-Rodríguez, M., Gómez-Martín, D. (2023) Disease activity is associated with changes in the innate immune function in patients with systemic lupus erythematosus. Clin Rheumatol. PMID: 37964076 https://doi.org/10.1007/s10067-023-06810-6
  2. Torres-Ruiz, J., Lomelín-Gascón, J., Lira-Luna, J., Vargas-Castro, A.S., Pérez-Fragoso, A., Nuñez-Aguirre, M., Alcalá-Carmona, B., Absalón-Aguilar, A., Balderas-Miranda, J.T., Maravillas-Montero, J.L., Mejía-Domínguez, N.R., Núñez-Álvarez, C., M., Llorente, L., Romero-Ramírez, S., Sosa-Hernández, V.A., Cervantes-Díaz, R., Juárez-Vega, G., Meza-Sánchez, D.E., Rull-Gabayet, M., Martínez-Juárez, L.A., Morales-Juárez, L., López-López, L.N., Negrete-Trujillo, J.A., Falcón-Lezama, J.A., Valdez-Vázquez, R.R., Gallardo-Rincón, H., Tapia-Conyer, R., Gómez-Martín, D. (2023) Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study. Infectious Diseases, 55:243-254, https://doi.org/10.1080/23744235.2022.2158217
  3. Castañeda-Sortibrán, A.N., Carballo-Ontiveros, M.C., Mejía-Domínguez, N.R., Echánove-Cuevas, D.A. (2023) Estudio exploratorio: Relación entre los beneficios percibidos por los estudiantes y los resultados de la Olimpiada Universitaria del Conocimiento en el área de Biología. Revista SENDA de Orientación y Atención Educativa, Segunda época, Número 6, mayo agosto 2023. https://www.orienta.unam.mx/senda/6/art3/
  4. Jiram Torres-Ruiz, Abdiel Absalón-Aguilar, Juan Alberto Reyes-Islas, Fabiola Cassiano-Quezada, Nancy R Mejía-Domínguez, Alfredo Pérez-Fragoso, José Luis Maravillas-Montero, Carlos Núñez-Álvarez, Guillermo Juárez-Vega, Alejandro Culebro-Bermejo, Diana Gómez-Martín, Peripheral expansion of myeloid-derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies, Rheumatology, Volume 62, Issue 2, February 2023, Pages 775-784, https://doi.org/10.1093/rheumatology/keac374
  5. Apodaca-Chávez, E., Demichelis-Gómez, R., Rosas-López, A., Mejía-Domínguez N.R., Galvan-López, I., Addorosio, M., Tracey, K.J., Valdés-Ferrer, S.I. (2022) Circulating HMGB1 is increased in myelodysplastic syndrome but not in other bone marrow failure syndromes: proof-of-concept cross-sectional study. Therapeutic Advances in Hematology;13. https://doi.org/10.1177/20406207221125990
  6. José C Páez-Franco, José L Maravillas-Montero, Nancy R Mejía-Domínguez, Jiram Torres-Ruiz, Karla M Tamez-Torres, Alfredo Pérez-Fragoso, Juan Manuel Germán-Acacio, Alfredo Ponce-de-León, Diana Gómez-Martín, Alfredo Ulloa-Aguirre. (2022) Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology. Plos one. https://doi.org/10.1371/journal.pone.0274910
  7. Torres-Ruiz J, Lomelín-Gascón J, Vargas-Castro AS, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Rull-Gabayet M, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez DE, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study. Front Immunol. 2022 Aug 15;13:943563. doi: 10.3389/fimmu.2022.943563.
  8. Echánove-Cuevas, D.A., Mejía-Domínguez N.R., Castañeda-Sortibrán, A.N. (2022) Is Mexico's population hesitant towards COVID-19 vaccines? A 2021 survey on different levels of hesitancy and its determinants. SSM - Population Health, https://doi.org/10.1016/j.ssmph.2022.101207
  9. Torres-Ruiz, J., Absalón-Aguilar, A., Reyes-Islas, J.A., Cassiano-Quezada, F., Mejía-Domínguez, N.R., Pérez-Fragoso, A., Maravillas-Montero, J., Núñez-Álvarez, C., Juárez-Vega, G., Culebro-Bermejo, A., Gómez-Martín, D. (2022) Peripheral expansion of myeloid derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies. Rheumatology, 29:keac374. https://doi.org/10.1093/rheumatology/keac374.
  10. Castro-Jiménez, T.K., Gómez-Legorreta, L.C., López-Campa, L.A., Martńez-Torres, V., Alvarado-Silva, M., Posadas-Mondragón, A., Díaz-Lima, N., Angulo-Mendez, H.A., Mejía-Domínguez, N.R., Vaca-Paniagua, F., Ávila-Moreno, F., García-Cordero, J., Cedillo-Barrón, L., Aguilar-Ruíz, S.R., Bustos-Arriaga, J. (2022) Variability in susceptibility to type I interferon response and subgenomic RNA accumulation between clinical isolates of dengue and Zika virus from Oaxaca Mexico correlate with replication efficiency in human cells and disease severity. Frontiers in Cellular and Infection Microbiology, 12. https://www.frontiersin.org/article/10.3389/fcimb.2022.890750
  11. Sosa-Hernández Víctor A., Romero-Ramírez Sandra, Cervantes-Díaz Rodrigo, Carrillo-Vázquez Daniel A., Navarro-Hernandez Itze C., Whittall-García Laura P., Absalón-Aguilar Abdiel, Vargas-Castro Ana S., Reyes-Huerta Raúl F., Juárez-Vega Guillermo, Meza-Sánchez David E., Ortiz-Navarrete Vianney, Torres-Ruiz Jiram, Mejía-Domínguez N.R., Gómez-Martín Diana, Maravillas-Montero José L. (2022) CD11c+ T-bet+ CD21hi B Cells Are Negatively Associated With Renal Impairment in Systemic Lupus Erythematosus and Act as a Marker for Nephritis Remission. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.892241
  12. Torres-Ruiz J, Lomelín-Gascón J, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez D, Rull-Gabayet M, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients. Clin Transl Med. 2021 Nov;11(11):e623. doi: 10.1002/ctm2.623. PMID: 34841707; PMCID: PMC8611773.
  13. Absalón-Aguilar, A., Rull-Gabayet, M., Pérez-Fragoso, A,. Mejía-Domínguez, N.R., Núñez-Álvarez, C., Kershenobich-Stalnikowitz, D., Sifuentes-Osornio, J., Ponce-de-León, A., González-Lara, F., Martín-Nares, E., Montesinos-Ramírez, S., Ramírez-Alemón, M., Ramírez-Rangel, P., Márquez, M.F., Plata-Corona, J.C., Juárez-Vega, G., Gómez-Martín, D., Torres-Ruiz, J. (2021) Colchicine Is Safe Though Ineffective in the Treatment of Severe COVID-19: a Randomized Clinical Trial (COLCHIVID). J Gen Intern Med. doi: 10.1007/s11606-021-07203-8. Epub ahead of print. PMID: 34755269.
  14. Mejía–Domínguez, N.R. Meave, J.A., Díaz-Ávalos, C., Gómez-Aparicio, L. (2021) Using spatial patterns of seeds and saplings to assess the prevalence of heterospecific replacements among cloud forest canopy tree species. JVS. 32(5):e13083. https://doi.org/10.1111/jvs.13083
  15. Torres-Ruiz, J., Absalón-Aguilar, A., Nuñez-Aguirre, M., Pérez-Fragoso, A,. Carrillo-Vázquez, D.A., Maravillas-Montero, J.L., Mejía-Domínguez, N.R., Llorente, L, Alcalá-Carmona, B., Lira-Luna, J., Núñez-Álvarez, C., Juárez-Vega, G., Meza-Sánchez, D., Hernández-Gilsoul, T., Tapia-Rodríguez, M., Gómez-Martín, D. (2021). Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity. Cells, 10(10):2545. https://doi.org/10.3390/cells10102545
  16. Torres-Ruiz, J., Pérez-Fragoso, A., Maravillas-Montero, J.L., Llorente, L., Mejía-Domínguez, N.R., Páez-Franco, J.C., Romero-Ramírez, S., Sosa-Hernández, V.A., Cervantes-Díaz, R., Absalón-Aguilar, A., Nuñez-Aguirre, M., Juárez-Vega, G., Meza-Sánchez, D., Kleinberg-Bild, A., Hernández-Gilsoul, T., Ponce-de-León, A., Gómez-Martín, D. (2021). Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Frontiers in Immunology:12, 3695. https://doi.org/10.3389/fimmu.2021.689966
  17. Calculadora de riesgo para COVID-19 (CLICOVID-19-SRS)
  18. Negrete-Najar, J.P., Juárez-Carrillo, Y., Gómez-Camacho, J., Mejía-Domínguez, N.R., Soto-Perez-de-Celis, E,. Avila-Funes, J.A., Navarrete-Reyes, A.P. (2021). Factors Associated with Nonattendance to a Geriatric Clinic among Mexican Older Adults. Gerontology. Aug 18:1-9. doi: 10.1159/000517919.
  19. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  20. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab. ,2021, 106(2):e534-e550.
  21. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.
  22. García-Osorio, B., Lomonte, B., Bénard-Valle, M., López de León, J., Román- Domínguez,L., Mejía-Domínguez, N.R., Lara-Hernández, F., Alagón, A., Neri- Castro, E. Ontogenetic changes in the venom of Metlapilcoatlus nummifer, the mexican jumping viper, Toxicon. 2020. 184: 204-214.
  23. Ochoa-Ochoa, L.M., Mejía-Domínguez, N.R., Velasco, J.A., Dimitrov, D., Marske, K.A. Dimensions of Amphibian alpha diversity in the New World. Journal of Biogeography, 2020, https://doi.org/10.1111/jbi.13948
  24. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  25. Ochoa-Ochoa, L.M., Mejía-Domínguez, N.R., Velasco, J. A., Marske, K.A., Rahbek, C. (2019) Amphibian functional diversity is related to high annual precipitation and low precipitation seasonality in the New World. Global Ecology and Biogeography, 29: Disponible en línea 29 de abril. https://doi.org/10.1111/geb.12926
  26. Mitre-Aguilar, I., Barrios-García, T., Ruíz-López, V., Cabrera-Quintero, A., Mejía-Domínguez, N., Ventura-Gallegos, J.L., Moreno-Mitre, D., Aranda-Gutierrez, A., Mejía-Rangel, J., Escalona-Guzmán, A., Chavarri-Guerra,Y., León Del Rio, A., Zentella-Dehesa, A., (2019). Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells. BMC Cancer,19:356. https://doi.org/10.1186/s12885-019-5563-y
  27. Martín-Manzo, M.V., Martín-Manzo, M.V., Lara, C., Vargas-de-Leon, C., Carrero, J., Queipo, G., Fonseca-Sanchez, M., Mejía-Domínguez, N.R., Kershenobich, D., Mummidi, S., Zentella-Dehesa, A., Hernandez, J. (2019) Interaction of Breast Cancer and Insulin Resistance on PD1 and TIM3 Expression in Peripheral Blood CD8 T Cells. Pathol. Oncol. Res. https://doi.org/10.1007/s12253-019-00610-7
  28. Torres-Ruiz, J., Mejía-Domínguez, N.R., Zentella-Dehesa, A. Ponce-de-León, A., Morales-Padilla, S.R., Vázquez-Rodríguez, R Alvarado-Lara, M.R., Reyna-de-la-Garza, R.A., Tapia-Rodríguez, M., Juárez-Vega, M., Merayo-Chalico, J., Alcocer-Varela, J., Gómez-Martín, D. (2019). The Systemic Lupus Erythematosus Infection Predictive Index (LIPI): A Clinical-Immunological Tool to Predict Infections in Lupus Patients. Frontiers in Immunology, 9: 3144. https://doi.org/10.3389/fimmu.2018.03144
  29. Lastra-German, I.K., Navarrete-Reyes, A.P., Mejía-Domínguez, N.R., Agreda-Vásquez, G.P. (2019). Adjusted chemotherapy according to frailty status in elderly patients with diffuse large B-cell lymphoma: Experience from a single referral center in Mexico City. Clinical Lymphoma, Myeloma and Leukemia, 19(2), e98-e106. https://doi.org/10.1016/j.clml.2018.11.013
  30. García-Jiménez, G., Zariñán, T., Rodríguez-Valentín, R., Mejía-Domínguez, N.R., Gutiérrez-Sagal, R., Hernández-Montes, G., Tovar, A., Arechavaleta-Velasco, F., Canto, I.P., Granados, J., Pellicer, A., Ulloa-Aguirre, A. (2018). Frequency of the T307A, N680S, and 29G> A Single Nucleotide Polymorphisms in the Follicle Stimulating Hormone Receptor in Hispanic Women. Reproductive Biology and Endocrinology, 16(1) https://doi.org/10.1186/s12958-018-0420-4.
  31. López-Castillo. L.S., Mejía-Domínguez. N.R., Resendis-Antonio, O. (2018) Single cell gene expression: a window to assess the intratumor heterogeneity in cancer. En: Cancer: a complex disease. Octavio Miramontes & Elena Álvarez-Buylla. (Eds.). CopIt-arXives. México. ISBN: 978-1-938128-15-8
  32. Gutiérrez-Prieto, A., Mejía-Domínguez, N.R., Díaz-Avalos, C. (2018) Prevalence of obesity in Mexico: model for imput values. pag. 161-164. En: Proceedings of the 8th International Workshop on Spatio-Temporal Modelling. METMA IX. 2018. http://metma2018.sfds.asso.fr/assets/Download/proceedingsMETMA9.pdf
  33. Allar-Oropeza, E.F., González-Medina, L.E., Mejía-Domínguez, N.R. (2018) Perspectiva Epidemiológica de la Obesidad, Síndrome metabólico, diabetes mellitus tipo 2 y Enfermedades Cardiovasculares. Red Universitaria de Aprendizaje (RUA). https://www.rua.unam.mx/portal/recursos/ficha/72937/perspectiva-epidemiologica-de-la-obesidad-de-la-diabetes-tipo-2-enfermedades-cardiovasculares-y-sindrome-metabolico-en-mexico
  34. Mejía-Domínguez, N.R., Díaz-Avalos, C. (2017) Predictive spatial models of obesity as risk factor for diabetes type 2 in Mexico. En: Abstract Book. GEOMED 2017 – International Conference on Spatial Statistics, Spatial Epidemiology & Spatial Aspects of Public Health. Porto, Portugal. http://www.i3s.up.pt/geomed2017/Geomed%202017_BOOK.pdf
  35. Juan P, Díaz-Ávalos C, Mejía-Domínguez NR, Mateu J. 2017. Spatial modelling of the presence of Chagas disease insect vectors in Argentina. Stochastic Environmental Research and Risk Assessment, 31:461–479.
  36. Ochoa-Ochoa LM, Mejía-Domínguez NR, Bezaury-Creel J. 2017. Priorización para la Conservación de los Bosques de Niebla en México. Ecosistemas, 26(2): 27-37.
  37. Mejía-Domínguez, N.R., Díaz-Avalos, C. Predictive spatial models of non-transmissible diseases in Mexico. pag. 201-203. Proceedings of the 8th International Workshop on Spatio-Temporal Modelling. METMA VIII. 2016. Iftimi, A., Mateu, J., Montes, F. Universitat de Valencia, Universidad Jaime I. ISBN: 978-84-608-8468-2, 2016.
  38. Juan, P., Díaz-Ávalos, C., Mejía-Domínguez, N.R., Mateu, J. (2016) Spatial modelling of the presence of Chagas disease insect vectors in Argentina. Stochastic Environmental Research and Risk Assessment. Disponible en línea 27-10-2016. DOI 10.1007/s00477-016-1340-5.

Previas

  1. Mejía-Domínguez, N.R., Díaz-Ávalos, C., Ochoa-Ochoa, L.M. (2014) Spatial autocorrelation in species distribution models: autologistic model with covariates vs. BioMod. En: Proceedings of the Seven International Workshop on Spatio-Temporal Modelling (METMA VII and GRASPA 14). Retrieved from http://hdl.handle.net/10446/31700
  2. Mejía-Domínguez, N.R., Díaz-Ávalos, C., Meave, J.A. (2012) Spatial relationships of litter composition and sapling community structure in a Neotropical cloud forest. En: Proceedings of GeoENV 2012, IX Conference on Geostatistical for Environmental Applications. González-Hernández, J.J. (Ed.). ISBN: 978-84-8363-924-5.
  3. Mejía-Domínguez, N.R., Meave, J.A., Díaz-Ávalos, C. (2012) Spatial structure of the abiotic environment and its association with seedling community structure and dynamics in a cloud forest. International Journal of Biometeorology, 56: 305-318. DOI 10.1007/s00484-011-0434-5.
  4. Mejía-Domínguez, N.R., Meave, J.A., Díaz-Ávalos, C., González, E. (2011) Individual canopy tree species effects on their immediate understory microsite and sapling community dynamics. Biotropica, 43 (5): 572-581. DOI: 10.1111/j.1744-7429.2010.00739.x.
  1. Teresa Zariñán, Jesús Espinal-Enriquez, Guillermo De Anda-Jáuregui, Saúl Lira-Albarrán, Georgina Hernández-Montes, Rubén Gutiérrez-Sagal, Rosa G. Rebollar-Vega, George R. Bousfield, Viktor Y. Butnev, Enrique Hernández-Lemus, Alfredo Ulloa-Aguirre.Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq. bioRxiv 2023.10.18.562995; doi: https://doi.org/10.1101/2023.10.18.562995
  2. Álvarez-Hilario LG, Salmerón-Bárcenas EG, Ávila-López PA, Hernández-Montes G, Aréchaga-Ocampo E, Herrera-Goepfert R, Albores-Saavedra J, Manzano-Robleda MDC, Saldívar-Cerón HI, Martínez-Frías SP, Thompson-Bonilla MDR, Vargas M, Hernández-Rivas R. Circulating miRNAs as Noninvasive Biomarkers for PDAC Diagnosis and Prognosis in Mexico. Int J Mol Sci. 2023 Oct 14;24(20):15193. doi: 10.3390/ijms242015193. PMID: 37894871; PMCID: PMC10607652.
  3. Delgadillo-Puga C, Sánchez-Castillo DR, Cariño-Cervantes YY, Torre-Villalvazo I, Tovar-Palacio C, Vásquez-Reyes S, Furuzawa-Carballeda J, Acevedo-Carabantes JA, Camacho-Corona MDR, Guzmán-Mar JL, Cisneros-Zevallos L, Tovar AR, Rebollar-Vega R, Hernández-Montes G, Ulloa-Aguirre A, Palacios-Gonzalez B, Noriega LG. Vachellia farnesiana Pods or a Polyphenolic Extract Derived from Them Exert Immunomodulatory, Metabolic, Renoprotective, and Prebiotic Effects in Mice Fed a High-Fat Diet. Int J Mol Sci. 2023 Apr 28;24(9):7984. doi: 10.3390/ijms24097984. PMID: 37175691; PMCID: PMC10178983.
  4. Dwivedi S, Hernández-Montes G, Montaño LF, Rendón-Huerta EP. Chromosomally Unstable Gastric Cancers Overexpressing Claudin-6 Disclose Cross-Talk between HNF1A and HNF4A, and Upregulated Cholesterol Metabolism. Int J Mol Sci. 2022 Nov 12;23(22):13977. doi: 10.3390/ijms232213977. PMID: 36430456; PMCID: PMC9694805.
  5. Ávila-González, D., Portillo, W., Barragán-Álvarez, C. P., Hernandez-Montes, G., Flores-Garza, E., Molina-Hernández, A., Díaz-Martínez, N. E., & Díaz, N. F. (2022). The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells. eLife, 11, e68035. https://doi.org/10.7554/eLife.68035
  6. Moreno-Santillán, D. D., Machain-Williams, C., Hernández-Montes, G., & Ortega, J. (2022). Transcriptomic analysis elucidates evolution of the major histocompatibility complex class I in neotropical bats. Journal of Mammalogy.
  7. P. A. Ávila-López, G. Guerrero, H. N. Nuñez-Martínez, C. A. Peralta-Alvarez, G. Hernández-Montes, L. G. Álvarez-Hilario, R. Herrera-Goepfert, J. Albores-Saavedra, N. Villegas-Sepúlveda, L. Cedillo-Barrón, A. E. Montes-Gómez, M. Vargas, M. Schnoor, F. Recillas-Targa & R. Hernández-Rivas. H2A.Z overexpression suppresses senescence and chemosensitivity in pancreatic ductal adenocarcinoma. Oncogene 40, 2065–2080 (2021). https://doi.org/10.1038/s41388-021-01664-1
  8. Lozano-Amado D, Ávila-López PA, Hernández-Montes G, Briseño-Díaz P, Vargas M, Lopez-Rubio JJ, Carrero JC, Hernández-Rivas R. A class I histone deacetylase is implicated in the encystation of Entamoeba invadens. Int J Parasitol. 2020, S0020-7519(20)30234-4. doi: 10.1016/j.ijpara.2020.05.014.
  9. Moreno-Santillán DD, Machain-Williams C, Hernández-Montes G, Ortega J. (2019) De Novo Transcriptome Assembly and Functional Annotation in Five Species of Bats. Sci Rep. Apr 17;9(1):6222. doi: 10.1038/s41598-019-42560-9. PubMed PMID: 30996290; PubMed Central PMCID: PMC6470166.
  10. García-Jiménez, G., Zariñán, T., Rodríguez-Valentín, R., Mejía-Domínguez, N.R., Gutiérrez-Sagal, R., Hernández-Montes, G., Tovar, A., Arechavaleta-Velasco, F., Canto, I.P., Granados, J., Pellicer, A., Ulloa-Aguirre, A. Frequency of the T307A, N680S, and 29G> A Single Nucleotide Polymorphisms in the Follicle Stimulating Hormone Receptor in Hispanic Women. Reproductive Biology and Endocrinology 16(1), 2018. https://doi.org/10.1186/s12958-018-0420-4.
  11. Contreras Alejandra V, Cocom-Chan Benjamin, Hernandez-Montes Georgina, Portillo-Bobadilla Tobias, Resendis-Antonio Osbaldo. (2016). Host-microbiome interaction and cancer: potential application in precision medicine. Frontiers in Physiology 7:606.

Previas

  1. Hernandez-Montes,G. Armenta-Medina,D. Perez-Rueda,E. 2013. Evolution of Metabolism: A Network Perspective of the Amino Acid Biosynthesis Pathways en: Dubitzky,W.e.a. Encyclopedia of Systems Biology. Springer. pags. 687-692
  2. Hernández-Montes G, Argüello JM, Valderrama B. Evolution and diversity of periplasmic proteins involved in copper homeostasis in gamma proteobacteria. BMC Microbiol. 2012 Nov 2;12:249. doi: 10.1186/1471-2180-12-249.
  3. Hernández-Montes G, Díaz-Mejía JJ, Pérez-Rueda E, Segovia L. The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. Genome Biol. 2008;9(6):R95. doi: 10.1186/gb-2008-9-6-r95.
  1. Morán P, Serrano-Vázquez A, Rojas-Velázquez L, González E, Pérez-Juárez H, Hernández EG, Padilla MLA, Zaragoza ME, Portillo-Bobadilla T, Ramiro M, Ximénez C. Amoebiasis: Advances in Diagnosis, Treatment, Immunology Features and the Interaction with the Intestinal Ecosystem. Int J Mol Sci. 2023 Jul 21;24(14):11755. doi: 10.3390/ijms241411755. PMID: 37511519; PMCID: PMC10380210.
  2. Pérez-Juárez, H., Serrano-Vázquez, A., Godínez‐Álvarez, H., González, E. A., Rojas-Velázquez, L., Morán, P., Portillo-Bobadilla, T., Ramiro, M., Hernández, E., Lau, C. B. S., Martínez, M., De Los Ángeles Padilla, M., Zaragoza, M. E., Taboada, B., Palomares, L. A., López, S., Alagón, A., Arias, C. F., & Ximénez, C. (2023). Longitudinal anti-SARS-CoV-2 antibody immune response in acute and convalescent patients. Frontiers in Cellular and Infection Microbiology, 13. https://doi.org/10.3389/fcimb.2023.1239700
  3. Rojas-Velázquez L, Morán P, Serrano-Vázquez A, Portillo-Bobadilla T, González E, Pérez-Juárez H, Hernández E, Partida-Rodríguez O, Nieves-Ramírez M, Padilla A, Zaragoza M and Ximénez C (2022) The regulatory function of Blastocystis spp. on the immune inflammatory response in the gut microbiome. Front. Cell. Infect. Microbiol. 12:967724. doi: 10.3389/fcimb.2022.967724
  4. Portillo Bobadilla Tobias, Pérez Hernández Bertha, Pérez Hernández Valentín y Hernández Guzmán Mario. Una Introducción a la bioinformática: avances en la biología y ciencias de la salud. Mens. Bioquim. 46 (2022): 1-12. ISSN-0188-137X.
  5. Ramírez-Carreto S, Vera-Estrella R, Portillo-Bobadilla T, Licea-Navarro A, Bernaldez-Sarabia J, Rudiño-Piñera E, Verleyen JJ, Rodríguez E, Rodríguez-Almazán C. Transcriptomic and Proteomic Analysis of the Tentacles and Mucus of Anthopleura dowii Verrill, 1869. Mar. Drugs. 17(8). Jul 25 pii: E436. https://doi.org/10.3390/md17080436, (2019).
  6. Liliana Rojas-Velázquez, Patricia Morán, Angélica Serrano-Vázquez, Leonardo D. Fernández, Horacio Pérez-Juárez, Augusto C. Poot-Hernández, Tobías Portillo, Enrique González, Eric Hernández, Oswaldo Partida-Rodríguez, Miriam E. Nieves-Ramírez, Ulises Magaña, Javier Torres, Luis E. Eguiarte, Daniel Piñero, Cecilia Ximénez. Genetic Diversity and Distribution of Blastocystis Subtype 3 in Human Populations, with Special Reference to a Rural Population in Central Mexico, BioMed Research International, ID 3916263, 7 pages, https://doi.org/10.1155/2018/3916263, (2018).
  7. Oswaldo Partida-Rodríguez, Angélica Serrano-Vázquez, Miriam E. Nieves-Ramírez, Patricia Moran, Liliana Rojas, Tobias Portillo, Enrique González, Eric Hernández, B. Brett Finlay, Cecilia Ximenez. Human Intestinal Microbiota: Interaction Between Parasites and the Host Immune Response, Archives of Medical Research, pags. 690-700, https://doi.org/10.1016/j.arcmed.2017.11.015, (2017).
  8. Contreras Alejandra V, Cocom-Chan Benjamin, Hernandez-Montes Georgina, Portillo-Bobadilla Tobias, Resendis-Antonio Osbaldo. (2016). Host-microbiome interaction and cancer: potential application in precision medicine. Frontiers in Physiology 7:606.

Previas

  1. Isheng J. Tsai, et al. (Consorcio Genoma Taenia solium). (2013) The genomes of four tapeworm species reveal adaptations to parasitism. Nature, 496: 57–63.
  2. Morán P, L.Rojas, R Cerritos, V Zermeño, A Valadez, G Montes de Oca, MA Reyes, E González, O Partida, E Hernánez, T Portillo, M Gudiño, M Ramiro and C Ximénez. (2013) Case report: Cutaneous amebiasis: the importance of molecular diagnosis of an emerging parasitic disease. Am J Trop Med Hyg, 88: 186–90.
  3. Meraz-Cruz N, A Alvarado-Delgado, MC Rodríguez-Gutierrez, T Portillo-Bobadilla, A Espejel-Nuñez, F Vadillo-Ortega. President's Plenary Session. (2013) Molecular characterization of a calcium-dependent matrix metalloproteinases complex associated to human amniochorion. Reproductive Sciences 16 (3): Supplement.
  4. H. Rosas-Vargas, B. Gómez-Diaz, L. Ruano-Calderón, F. Fernandez-Valverde, B. Roque-Ramírez, T. Portillo-Bobadilla, R.M. Ordoñez-Razo, F. Minauro-Sanmiguel, R. Coral-Vazquez. (2007) Dysferlin Homozygous Mutation G1418D Causes Limb-Girdle Type 2B in a Mexican Family. Genetic Testing 11(4): 391-396.
  5. Portillo T., González G. y Moreno J. (2005) Evaluación del software de proteínas Interacciones Macromoleculares. Rev. Soc. Quím. Méx. (Número Especial 4) 49: 220.

º Laboratorio de Genómica

  1. Torres-Morán, M., Franco-Álvarez, A. L., Rebollar-Vega, R., & Hernández-Ramírez, L. C. (2023). Hotspots of somatic genetic variation in pituitary neuroendocrine tumors. Cancers, 15(23), 5685. https://doi.org/10.3390/cancers15235685
  2. Rebollar-Vega, R., Zuarth-Vázquez, J. M., & Hernández-Ramírez, L. C. (2023). Clinical spectrum of USP8 pathogenic variants in Cushing’s Disease. Archives of Medical Research, 54(8), 102899. https://doi.org/10.1016/j.arcmed.2023.102899
  3. Franco-Álvarez, A. L., Moran, M., Rebollar-Vega, R. G., Pankratz, N., Lane, J., Faucz, F. R., Chittiboina, P., Kay, D. M., Mills, J. L., Stratakis, C. A., & Hernández-Ramírez, L. C. (2023). OR2802 a novel CABLES1 missense variant associated with Cushing’s disease disrupts protein structure and stability. Journal of the Endocrine Society, 7(Supplement_1). https://doi.org/10.1210/jendso/bvad114.1364
  4. Julia M Zuarth-Vazquez, Rosa G Rebollar-Vega, Claudia Ramírez-Rentería, Wellbert E Hernández-Núñez, Mariana Torres-Morán, Alexa L Franco-Álvarez, Jocelyn Eseiza-Acevedo, Mercedes Aguilar-Soto, Daniel Cuevas-Ramos, Ernesto Sosa-Eroza, Moises Mercado, Armando Gamboa-Dominguez, Laura C Hernández-Ramírez, SAT603 A Heterogeneous Genetic Background Underlies Familial And Young-onset Pituitary Tumors, Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.1336, https://doi.org/10.1210/jendso/bvad114.1336
  5. Trivellin, G., Daly, A., Hernández-Ramírez, L. C., Araldi, E., Tatsi, C., Dale, R. K., Fridell, G., Mittal, A., Faucz, F. R., Iben, J. R., Li, T., Vitali, E., Stojilković, S. S., Kamenický, P., Villa, C., Baussart, B., Chittiboina, P., Toro, C., Gahl, W. A., Stratakis, C. A. (2023). Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1166076
  6. Hernández-Ramírez, L. C., Pankratz, N., Lane, J., Faucz, F. R., Chittiboina, P., Kay, D. M., Beethem, Z. T., Mills, J. L., & Stratakis, C. A. (2022). Genetic drivers of Cushing’s disease: Frequency and associated phenotypes. Genetics in Medicine, 24(12), 2516-2525. https://doi.org/10.1016/j.gim.2022.08.021
  7. Chittiboina, P., Kay, D. M., Mills, J. L., Stratakis, C. A., Hernández-Ramírez, L. C., Pankratz, N., Lane, J. W., & Faucz, F. R. (2022). RF01 | PMON167 isolated Cushing’s disease associated with rare germline SDHX variants. Journal of the Endocrine Society, 6(Supplement_1), A575–A576. https://doi.org/10.1210/jendso/bvac150.1194
  8. Laura Hernández-Ramírez, Jesús Espinal-Enriquez, Guillermo D Anda-Jáuregui, Georgina Hernández-Montes, Teresa Zariñán, Rubén Gutierrez-Sagal, Rosa G Rebollar-Vega, George R Bousfield, Viktor Y Butnev, James A Dias, Enrique Hernández-Lemus, Alfredo Ulloa-Aguirre, PMON183 Impact of Small Negative Allosteric Modulators (NAM) of the Follicle-stimulating Hormone (FSH) Receptor on the Dynamics of the Transcriptome in Rat Granulosa Cells Exposed to Different FSH Glycosylation Variants., Journal of the Endocrine Society, Volume 6, Issue Supplement_1, November-December 2022, Pages A589–A590, https://doi.org/10.1210/jendso/bvac150.1221
  9. Laura C Hernandez-Ramírez. Determinants of Clinical Behavior and Prognosis in Cushing's Disease: A Quest for Useful Biomarkers. Revista de investigación clínica 2022; 74:244-257.
  10. Silva TS, Faucz FR, Hernández-Ramírez LC, Pankratz N, Lane J, Kay DM, Lyra A, Kochi C, Stratakis CA, Longui CA, Mills JL. Whole exome sequencing in patients with ectopic posterior pituitary. J Endocr Soc 2022; 6:1-12.

Previas

  1. Chasseloup F, Pankratz N, Lane J, Faucz FR, Keil MF, Chittiboina P, Kay DM, Hussein Tayeb T, Stratakis CA, Mills JL, Hernández-Ramírez LC. Germline CDKN1B loss of function variants cause pediatric Cushing’s disease with or without an MEN4 phenotype J Clin Endocrinol Metab 2020; 105:1-23.
  2. Hernández-Ramírez LC, Morgan RML, Barry S, D'Acquisto F, Prodromou C, Korbonits M. Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland. Oncotarget 2018;9:9177-9198.
  3. Hernández-Ramírez LC, Tatsi C, Lodish MB, Faucz FR, Pankratz N, Chittiboina P, Lane J, Kay DM, Valdés N, Dimopoulos A, Mills JL, Stratakis CA. Corticotropinoma as a component of Carney complex. Journal of the Endocrine Society 2017;1:918-925.
  4. Hernández-Ramírez LC, Gam R, Valdés N, Lodish M, Pankratz N, Balsalobre A, Gauthier Y, Faucz FR, Trivellin G, Chittiboina P, Lane J, Kay DM, Dimopoulou A, Gaillard S, Neou M, Bertherat J, Assié G, Villa C, Mills JL, Drouin J, Stratakis CA. Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease. Endocr Relat Cancer 2017;24:379-392.
  5. Faucz FR, Tirosh A, Tatsi C, Berthon A, Hernández-Ramírez LC, Settas N, Angelousi A, Correa R, Papadakis GZ, Chittiboina P, Quezado M, Pankratz N, Lane J, Dimopoulos A, Mills JL, Lodish M, Stratakis CA. Somatic USP8 gene mutations are a common cause of pediatric Cushing disease. J Clin Endocrinol Metab 2017;102:2836-2843.
  6. Radian S, Diekmann Y, Gabrovska P, Holland B, Bradley L, Wallace H, Stals K, Bussell AM, McGurren K, Cuesta M, Ryan AW, Hérincs M, Hernández-Ramírez LC, Holland A, Samuels J, Aflorei ED, Barry S, Dénes J, Pernicova I, Stiles CE, Trivellin G, McCloskey R, Ajzensztejn M, Abid N, Akker SA, Mercado M, Cohen M, Thakker RV, Baldeweg S, Barkan A, Musat M, Levy M, Orme SM, Unterlander M, Burger J, Kumar AV, Ellard S, McPartlin J, McManus R, Linden GJ, Atkinson B, Balding DJ, Agha A, Thompson CJ, Hunter SJ, Thomas MG, Morrison PJ, Korbonits M. increased population risk of AIP-related acromegaly and gigantism in Ireland. Human Mutation 2017; 38:78-85.
  7. Hernández-Ramírez LC, Martucci F, Morgan RM, Trivellin G, Tilley D, Ramos-Guajardo N, Iacovazzo D, D'Acquisto F, Prodromou C, Korbonits M. Rapid proteasomal degradation of mutant proteins is the primary mechanism leading to tumorigenesis in patients with missense AIP mutations. J Clin Endocrinol Metab. 2016;101:3144-54.
  8. Iacovazzo D, Caswell R, Bunce B, Jose S, Yuan B, Hernández-Ramírez LC, Kapur S, Caimari F, Evanson J, Ferraù F, Dang MN, Gabrovska P, Larkin SJ, Ansorge O, Rodd C, Vance ML, Ramírez-Rentería C, Mercado M, Goldstone AP, Buchfelder M, Burren CP, Gurlek A, Dutta P, Choong CS, Cheetham T, Trivellin G, Stratakis CA, Lopes MB, Grossman AB, Trouillas J, Lupski JR, Ellard S, Sampson JR, Roncaroli F, Korbonits M. Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathol Commun. 2016;4:56.
  9. Hernández-Ramírez LC, Gabrovska P, Dénes J, Stals K, Trivellin G, Tilley D, Ferraù F, Evanson J, Ellard S, Grossman AB, Roncaroli F, Gadelha MR, Korbonits M, International FIPA Consortium (Agha A, Akker SA, Aflorei ED, Alföldi S, Arlt W, Atkinson B, Aulinas-Masó A, Aylwin SJ, Backeljauw PF, Badiu C, Baldeweg S, Bano G, Barkan A, Barwell J, Bernal-González C, Besser G, Bevan JS, Blair J, Bouloux P, Bradley L, Buchfelder M, Cakir M, Canham N, Carroll P, Chahal HS, Cheetham T, Chentli F, Clayton RN, Cohen M, Cole T, Courtney H, Crowne E, Cuthbertson D, Dal J, Dalantaeva N, Daousi C, Darzy K, Dattani M, Davies JH, Davis J, De Castro M, De Marinis L, Drake W, Dutta P, Dzeranova L, Edén-Engström B, Eeles R, Elfving M, Elston M, Emmerson L, Fersht N, Fica S, Fischli S, Flanagan D, Fleseriu M, Freda PU, Friedman T, Frohman LA, Gallego P, Gevers E, Gláz E, Goldman JA, Goldstone AP, Goth M, Greenhalgh L, Grieve J, Guitelman M, Gürlek A, Gurnell M, Horvath K, Howlett TA, Höybye C, Hunter S, Iacovazzo D, Igaz P, Inder WJ, Iwata T, Izatt L, Jagadeesh S, Kaltsas G, Kaplan F, Karavitaki N, Kastelan D, Katz M, Kearney T, Khoo B, Kiraly-Borri C, Knispelis R, Kovács GL, Kumar AV, Laws ER Jr, Lechan RM, Levy J, Lewandowski K, Lo J, Maartens N, Matsuno A, McGowan B, McQuaid SE, Medic-Stojanoska M, Mercado-Atri M, Mezősi E, Miljic D, Miller KK, Modenesi S, Molitch ME, Monson J, Morris DG, Morrison PJ, Munir A, Murray RD, Musat M, Musolino N, Nachtigall L, Newell-Price J, Ogilvie A, Orme SM, Paşcanu I, Patócs A, Patterson C, Pearce SH, Pecori Giraldi F, Pfeifer M, Popovic V, Poplawski N, Powell M, Pullan P, Quinton R, Radian S, Randeva H, Ribeiro-Oliveira A Jr, Rodd C, Ryan F, Salvatori R, Schöfl C, Shears D, Shotliff K, Soares BS, Spada A, Sperber J, Spoudeas HA, Stewart S, Storr H, Strasburger C, Street ME, Swords F, Thakker RV, Tham E, Thompson C, Thorner MO, Tóth M, Trainer PJ, Tsagarakis S, Tzanela M, Vadász J, Vaks V, Verkauskiene R, Wass JA, Webb SM, Weber A, Yamada S, Yarman S, Yeoh P, Yoshimoto K, Zammitt NN) Landscape of familial isolated and young-onset pituitary adenomas: prospective diagnosis in AIP mutation carriers. J Clin Endocrinol Metab. 2015;100:E1242-1254.
  10. Morgan RM, Hernández-Ramírez LC, Trivellin G, Zhou L, Roe SM, Korbonits M, Prodromou C. Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal alpha-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition. PLoS One 2012;7:e53339.
  1. Torres-Flores, U., Díaz-Espinosa, F., López-Santaella, T., Rebollar-Vega, R., Vázquez-Jiménez, A., Taylor, I., Ortíz, R., Echeverría, O. M., Vázquez-Nin, G. H., Gutiérrez-Ruíz, M., De La Rosa-Velázquez, I. A., Reséndis-Antonio, O., & Hernández-Hernández, A. (2023). Spermiogenesis alterations in the absence of CTCF revealed by single cell RNA sequencing. Frontiers in Cell and Developmental Biology, 11. https://doi.org/10.3389/fcell.2023.1119514
  2. Delgadillo-Puga, C., Sánchez-Castillo, D. R., Cariño-Cervantes, Y. Y., Torre-Villalvazo, I., Tovar-Palacio, C., Vásquez-Reyes, S., Furuzawa-Carballeda, J., Acevedo-Carabantes, J. A., Del Rayo Camacho-Corona, M., Guzmán-Mar, J. L., Cisneros-Zevallos, L., Tovar, A. R., Rebollar-Vega, R., Hernández-Montes, G., Ulloa-Aguirre, A., Palacios-González, B., & Noriega, L. G. (2023). Vachellia farnesiana Pods or a Polyphenolic Extract Derived from Them Exert Immunomodulatory, Metabolic, Renoprotective, and Prebiotic Effects in Mice Fed a High-Fat Diet. International Journal of Molecular Sciences, 24(9), 7984. https://doi.org/10.3390/ijms24097984
  3. Arriaga-Canon, C., Contreras-Espinosa, L., Rebollar-Vega, R., Montiel-Manríquez, R., Cedro-Tanda, A., García-Gordillo, J. A., Álvarez-Gómez, R. M., Jiménez-Trejo, F., Castro-Hernández, C., & Herrera, L. A. (2022). Transcriptomics and RNA-Based therapeutics as potential approaches to manage SARS-COV-2 infection. International Journal of Molecular Sciences, 23(19), 11058. https://doi.org/10.3390/ijms231911058
  4. Hernández-Hernández, A., López-Santaella, T., Torres-Caballero, A., Serrato, A., Torres-Flores, U., Montesinos-Valencia, D., De León, F. C., González-Carranza, V., Torres-García, S., Rebollar-Vega, R., De La Rosa-Velázquez, I. A., Ortíz, R., Pérez-Ramírez, M., García-Hernández, N., García-Méndez, A., & Arenas-Huertero, F. (2022). The transcriptomic landscape of pediatric astrocytoma. International Journal of Molecular Sciences, 23(20), 12696. https://doi.org/10.3390/ijms232012696
  5. Contreras-Espinosa L, Alcaraz N, De La Rosa-Velázquez IA, Díaz-Chávez J, Cabrera-Galeana P, Rebollar-Vega R, Reynoso-Noveron N, Maldonado-Martínez HA, González-Barrios R, Montiel-Manríquez R, Bautista-Sánchez D, Castro-Hernández C, Álvarez-Gómez RM, Jiménez-Trejo F, Tapia-Rodríguez M, García-Gordillo J, Pérez-Rosas A, Bargallo-Rocha E, Arriaga-Canon C, Herrera LA. Transcriptome Analysis Identifies GATA3-AS1 as a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients. J Mol Diagn. 2021 Aug
  6. Flores-León M, Alcaraz N, Pérez-Domínguez M, Torres-Arciga K, Rebollar-Vega R, De la Rosa-Velázquez IA, Arriaga-Canon C, Herrera LA, Arias C, González-Barrios R. Transcriptional Profiles Reveal Deregulation of Lipid Metabolism and Inflammatory Pathways in Neurons Exposed to Palmitic Acid. Mol Neurobiol. 2021 Jun 21
  7. Romero-Cordoba SL, Salido-Guadarrama I, Rebollar-Vega R, Bautista-Piña V, Domínguez-Reyes C, Tenorio-Torres A, Villegas-Carlos F, Fernández-López JC, Uribe-Figueroa L, Alfaro-Ruiz L, Hidalgo-Miranda A. Comprehensive omic characterization of breast cancer in Mexican-Hispanic women. Nat Commun. 2021 Apr 14; 12(1):2245.
  8. Cedro-Tanda A, Ríos-Romero M, Romero-Córdoba S, Cisneros-Villanueva M, Rebollar-Vega RG, Alfaro-Ruiz LA, Jiménez-Morales S, Domínguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Bautista-Piña V, Beltrán-Anaya FO, Hidalgo-Miranda A. A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype. Sci Rep. 2020 Aug 4; 10(1):13146.
  9. Zyanya Lucia Zatarain Barrón, Brenda Marquina-Castillo, Jorge Alberto Barrios-Payan, Fernanda Cornejo, Otoniel Maya-Lucas, Gamaliel López-Leal, Camilo Molina, Richard M Anthony, Adrián Ochoa-Leyva, Inti Alberto de la Rosa, Rosa Gloria Rebollar-Vega, Robin Mark Warren, Rogelio Hernández Pando, Dulce Adriana Mata, Dick van Soolingen. Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis. Front. Immunol., 19 May 2020
  10. Beltrán-Anaya FO, Romero-Córdoba S, Rebollar-Vega R, Arrieta O, Bautista-Piña V, Dominguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Alfaro-Riuz L, Jiménez-Morales S, Cedro-Tanda A, Ríos-Romero M, Reyes-Grajeda JP, Tagliabue E, Iorio MV, Hidalgo-Miranda A. Expression of long non-coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple-negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell death. Mol Oncol. 2019 Apr; 13(4):909-927. doi: 10.1002/1878-0261.12446. Epub 2019 Feb 9.
  11. Fernández-Lopez JC, Romero-Córdoba S, Rebollar-Vega R, Alfaro-Ruiz LA, Jiménez-Morales S, Beltrán-Anaya F, Arellano-Llamas R, Cedro-Tanda A, Rios-Romero M, Ramirez-Florencio M, Bautista-Piña V, Dominguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Hidalgo-Miranda A. Population and breast cancer patients' analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population. Hum Genomics. 2019 Jan 10; 13(1):3. doi: 10.1186/s40246-018-0188-9.
  12. Rebollar-Vega RG, Arriaga-Canon C and de la Rosa-Velázquez IA. Clinical Applications of Next-Generation Sequencing. Rev Invest Clin. 2018; 70(4):153-157.
  13. Arellano-Llamas R, Alfaro-Ruiz L, Arriaga Canon C, Imaz Rosshandler I, Cruz-Lagunas A, Zúñiga J, Rebollar Vega R, Wong CW, Maurer-Stroh S, Romero Córdoba S, Liu ET, Hidalgo-Miranda A, Vázquez-Pérez JA. Molecular features of influenza A (H1N1) pdm09 prevalent in Mexico during winter seasons 2012-2014. PLoS One. 2017 Jul 10;12(7)

Previas

  1. Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, Bautista-Piña V, Duke F, Francis J, Jung J, Maffuz-Aziz A, Onofrio RC, Parkin M, Pho NH, Quintanar-Jurado V, Ramos AH, Rebollar-Vega R, Rodriguez-Cuevas S, Romero-Cordoba SL, Schumacher SE, Stransky N, Thompson KM, Uribe-Figueroa L, Baselga J, Beroukhim R, Polyak K, Sgroi DC, Richardson AL, Jimenez-Sanchez G, Lander ES, Gabriel SB, Garraway LA, Golub TR, Melendez-Zajgla J, Toker A, Getz G, Hidalgo-Miranda A, Meyerson M. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012 Jun 20; 486(7403):405-9.
  2. Romero-Cordoba S, Rodriguez-Cuevas S, Rebollar-Vega R, Quintanar-Jurado V, Maffuz-Aziz A, Jimenez-Sanchez G, Bautista-Piña V, Arellano-Llamas R, Hidalgo-Miranda A. Identification and pathway analysis of microRNAs with no previous involvement in breast cancer. PLoS One. 2012;7(3):e31904.
  3. Heres-Pulido ME, Dueñas-García I, Castañeda-Partida L, Santos-Cruz LF, Vega-Contreras V, Rebollar-Vega R, Gómez-Luna JC, Durán-Díaz A. Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster. Food Chem Toxicol. 2010 Jan;48(1):120-8.

º Laboratorio de Biología Molecular y Cultivo Celular

  1. Cruz-Huerta, E., Zariñán, T., Enríquez, J., Ulloa-Aguirre, A., & Gutiérrez-Sagal, R. (2024). Estrogen regulated transcription of the non-estrogen-regulated hamster uteroglobin gene in MCF-7 cells. General and Comparative Endocrinology, 347, 114424. https://doi.org/10.1016/j.ygcen.2023.114424
  2. Jardón-Valadez, E., & Ulloa-Aguirre, A. (2024). Tracking conformational transitions of the gonadotropin hormone receptors in a bilayer of (SDPC) poly-unsaturated lipids from all-atom molecular dynamics simulations. PLOS Computational Biology, 20(1), e1011415. https://doi.org/10.1371/journal.pcbi.1011415
  3. Ulloa-Aguirre, A., Zariñán, T., Espinal-Enríquez, J., De Anda-Jáuregui, G., Lira-Albarrán, S., Hernández-Montes, G., Rebollar-Vega, R., Bousfield, G. R., Butnev, V. Y., & Hernández-Lemus, E. (2023). Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq. bioRxiv (Cold Spring Harbor Laboratory). https://doi.org/10.1101/2023.10.18.562995
  4. Alfredo Ulloa-Aguirre, Teresa Zariñán, Rubén Gutiérrez-Sagal, Selvaraj Nataraja, Henry N Yu, Eduardo Jardón-Valadez, OR03-01 Functional Rescue Of Trafficking-Defective Mutant Follicle-Stimulating Hormone Receptors (FSHR) Leading To Premature Ovarian Failure With The Pharmacoperone CAN1405, Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.1557, https://doi.org/10.1210/jendso/bvad114.1557
  5. Lispi M, Humaidan P, Bousfield GR, D’Hooghe T, Ulloa-Aguirre A. Follicle-Stimulating Hormone Biological Products: Does Potency Predict Clinical Efficacy? International Journal of Molecular Sciences. 2023; 24(10):9020. https://doi.org/10.3390/ijms24109020
  6. Delgadillo-Puga, C., Sánchez-Castillo, D. R., Cariño-Cervantes, Y. Y., Torre-Villalvazo, I., Tovar-Palacio, C., Vásquez-Reyes, S., Furuzawa-Carballeda, J., Acevedo-Carabantes, J. A., Del Rayo Camacho-Corona, M., Guzmán-Mar, J. L., Cisneros-Zevallos, L., Tovar, A. R., Rebollar-Vega, R., Hernández-Montes, G., Ulloa-Aguirre, A., Palacios-González, B., & Noriega, L. G. (2023). Vachellia farnesiana Pods or a Polyphenolic Extract Derived from Them Exert Immunomodulatory, Metabolic, Renoprotective, and Prebiotic Effects in Mice Fed a High-Fat Diet. International Journal of Molecular Sciences, 24(9), 7984. https://doi.org/10.3390/ijms24097984
  7. Ulloa-Aguirre, A., Zariñán, T., Espinal-Enríquez, J., De Anda-Jáuregui, G., Lira-Albarrán, S., Hernández-Montes, G., Rebollar-Vega, R., Bousfield, G. R., Butnev, V. Y., & Hernández-Lemus, E. (2023). Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq. bioRxiv (Cold Spring Harbor Laboratory). https://doi.org/10.1101/2023.10.18.562995
  8. Jardón-Valadez, E., & Ulloa-Aguirre, A. (2023). Searching deeply into the conformational space of glycoprotein hormone receptors. Molecular dynamics of the human follitropin and lutropin receptors within a bilayer of (SDPC) poly-unsaturated lipids. bioRxiv (Cold Spring Harbor Laboratory). https://doi.org/10.1101/2023.08.09.552573
  9. Manusov, E. G., Reininger, B. M., Ulloa-Aguirre, A., & Williams-Blangero, S. (2022). The biology and management of chronic diseases in Mexican Americans. Frontiers in Medicine, 9. https://doi.org/10.3389/fmed.2022.1095203
  10. Laura Hernández-Ramírez, Jesús Espinal-Enriquez, Guillermo D Anda-Jáuregui, Georgina Hernández-Montes, Teresa Zariñán, Rubén Gutierrez-Sagal, Rosa G Rebollar-Vega, George R Bousfield, Viktor Y Butnev, James A Dias, Enrique Hernández-Lemus, Alfredo Ulloa-Aguirre, PMON183 Impact of Small Negative Allosteric Modulators (NAM) of the Follicle-stimulating Hormone (FSH) Receptor on the Dynamics of the Transcriptome in Rat Granulosa Cells Exposed to Different FSH Glycosylation Variants., Journal of the Endocrine Society, Volume 6, Issue Supplement_1, November-December 2022, Pages A589-A590, https://doi.org/10.1210/jendso/bvac150.1221
  11. Páez-Franco, J. C., Maravillas-Montero, J. L., Mejía-Domínguez, N. R., Torres-Ruíz, J., Tamez-Torres, K. M., Pérez-Fragoso, A.,Germán-Acacio, J. M. , Ponce-De-León, A., Gómez-Martín, D., & Ulloa-Aguirre, A. (2022). Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology. PLOS ONE, 17(9), e0274910. https://doi.org/10.1371/journal.pone.0274910
  12. Jardón-Valadez, E., Ulloa-Aguirre, A., Portillo-Bobadilla, T., & Villavicencio-Pulido, G. (2022). Reshaping the dynamics of follicle-stimulant hormone receptor models in polyunsaturated lipid bilayers. Calculation of conformational free energy landscapes of α-helical domains from all-atom MD simulations. bioRxiv (Cold Spring Harbor Laboratory). https://doi.org/10.1101/2022.06.06.494945
  13. Ulloa-Aguirre A, Zariñán T, Gutiérrez-Sagal, Tao, Y-X. Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases. Frontiers in Endocrinology, 13:934685, 2022.
  14. Manzi L, Sepe N, Migliaccio W, Lanzoni L, Iozzino L, D’Angelo F, Colarusso L, Montenegro S, Angelo Palmese A, Thomas D’Hooghe T, Alfredo Ulloa-Aguirre A, Koloda Y, Lispi M. Comparative assessment of the structural features of originator recombinant follitropion alfa versus recombinant human follitropin alfa biosimilar preparations approved in non-european regions. International Journal of Molecular Sciences, 23(12):6762, 2022.
  15. Vásquez-Reyes S, Vargas-Castillo A, Noriega LG, Velázquez-Villegas LA, Pérez B, Sánchez-Tapia M, Ordaz G, Suárez-Monroy R, Ulloa-Aguirre A, Offner H, Torres N, Tovar AR. Genistein stimulation of white adipose tissue thermogenesis is partially dependent on GPR30 in mice. Molecular Nutrition & Food Research, 2022: 2100838.
  16. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab., 2021, 106(2):e534-e550.
  17. Páez-Franco J.C., Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  18. Dias JA, Ulloa-Aguirre A. New human follitropin preparations: How glycan structural differences may affect biochemical and biological function and clinical effect. Frontiers in Endocrinology 12:636038, 2021.
  19. Gamba G, Wolpert-Barraaza E, Loria A, Ulloa-Aguirre A. The evolving history of the Revista de Investigación Clínica. Revista de Investigación Clínica (Mex) 73:270-279, 2021.
  20. Ulloa-Aguirre A, Ocaña-Ocaña L, Selman AM. Revista de Investigación Clínica -Clinical and Translational Investigation-: Editors’ choces 6 years later. Revista de Investigación Clínica (Mex) 73:288-296, 2021.
  21. González-Duarte A, Ulloa-Aguirre A. A brief journey through protein misfolding in transthyretin amyloidosis (ATTR amyloidosis). International Journal of Molecular Sciences 22:13158, 2021.
  22. Ulloa-Aguirre A, Zariñán T, Jardón-Valadez E. Misfolded G protein-coupled receptors and endocrine disease. Molecular mechanisms and therapeutic prospects. Int J Mol Sci., International Journal of Molecular Sciences 22:12329, 2021.
  23. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  24. Esparza-López J, Alvarado-Muñoz JF, Escobar-Arriaga E, Ulloa-Aguirre A, Ibarra-Sánchez MJ. Metformin reverses mesenchymal phenotype of primary breaset cancer cells through STAT3/NF-kB pathways. BMC Cancer, 19:728, 2019.
  25. Ulloa-Aguirre A, Janovick J-A. Modulation of Proteostasis and Protein Trafficking as an Appealing Therapeutic Avenue for Misfolded G Protein-Coupled Receptors Causing Disease in Humans. Emerging Topics in Life Sciences, 3:39-52, 2019.
  26. Ulloa-Aguirre A, Zariñán T, Jardón-Valadez E, Gutiérrez-Sagal R, Dias JA. Structure-function relationships of the follicle-stimulating hormone receptor. Frontiers in Endocrinology 9:707 (1-17), 2018.
  27. Jardón-Valadez E, Castillo-Guajardo D, Martínez-Luis I, Ulloa-Aguirre A. Molecular dynamics simulation of the follicle-stimulating hormone receptor. Understanding the conformational dynamics of receptor variants at position D408 and N680 from in silico analysis. Plos One 13(11):e0207526 (1-22), 2018.
  28. Hou ZH, Ulloa-Aguirre A, Tao Y-X-. Pharmacoperone drugs: targeting misfolded proteins causing lysosomal storage-, ion channels-, and G protein-coupled receptors-associated conformational disorders. Expert Review of Clinical Pharmacology, 11(6):611-624, 2018.
  29. Ortega-Olvera C, Ulloa-Aguirre A, Ángeles-Llerenas A, Mainero Ratchelous F, González-Acevedo C, Hernández Blanco ML, Ziv E, Avilés-Santa L, Pérez-Rodríguez Torres-Mejía G. Thyroid hormones and breast cancer association according to menopausal status and body mass index. Breast Cancer Research 20:94, 2018.
  30. García-Jiménez, G., Zariñán, T., Rodríguez-Valentín, R., Mejía-Domínguez, N.R., Gutiérrez-Sagal, R., Hernández-Montes, G., Tovar, A., Arechavaleta-Velasco, F., Canto, I.P., Granados, J., Pellicer, A., Ulloa-Aguirre, A. Frequency of the T307A, N680S, and 29G> A Single Nucleotide Polymorphisms in the Follicle Stimulating Hormone Receptor in Hispanic Women. Reproductive Biology and Endocrinology 16(1), 2018. https://doi.org/10.1186/s12958-018-0420-4.
  31. Domíguez-López P, Diaz-Cueto L, Arechavaleta-Velasco-M, Caldiño-Soto F, Ulloa-Aguirre A, Arechavaleta-Velasco F. The follicle-stimulating hormone receptor AsnSer680 polymorphism is associated with preterm birth in Hispanic women. Journal of Maternal-Fetal & Neonatal Medicine, 2018. http://dx.doi.org/10.1080/14767058.2017.1292245.
  32. Ulloa-Aguirre A, Zariñán T, Gutiérrez-Sagal R, and Dias JA. Intracellular Trafficking of Gonadotropin Receptors in Health and Disease. Handbook of Experimental Pharmacology 2017 (DOI 10.1007/164_2017_49)
  33. Ulloa-Aguirre A, Conn, P.M. Pharmacoperones as a New Therapeutic Approach: In vitro Identification and In vivo Validation of New Bioactive Molecules. Current Drug Targets, 17:1471-1481, 2016.
  34. Melo-Nava B, Casas-González P, Pérez-Solís M, Castillo-Badillo J, Maravillas-Montero JL, Jardón-Valadez E, Zariñán T, Aguilar-Rojas A, Gallay N, Reiter E, Ulloa-Aguirre A. Role of cysteine residues in the carboxyl-terminus of the follicle-stimulating hormone receptor in intracellular traffic and postendocytic processing. Frontiers in Cell and Developmental Biology, 4:76, 2016.
  35. Ulloa-Aguirre A, Zariñán T. The follitropin receptor. Matching structure and function. Molecular Pharmacology, 90:596-608, 2016.
  36. Mazurkiewicz JE, Herrick-Davis K, Barroso M, Ulloa-Aguirre A, Lindau-Shepard B, Thomas RM, Dias J. Single molecule analyses of fully functional fluorescent protein tagged follictropin receptor reveals homodimerization and specific heterodimerization with lutropin receptor. Biology of Reproduction, 92(4):100, 1-12, 2015
  37. Ulloa-Aguirre A, Reiter E, Bousfield G, Dias JA, Huhtaniemi I. Constitutive activity in gonadotropin receptors. Advances in Pharmacology, 70:37-79, 2014.
  38. Conn PM, Smithson DC, Hodder PS, Stewart MD, Behringer RR, Smith E, Ulloa-Aguirre A, Janovick JA. Transitioning pharmacoperones to therapeutic use: In vivo proof-of-principle and design of high throughput screens. Pharmacol Res, 83C:38-51, 2014.

Contribuciones en libros, capítulos y monografías

  1. Narayan P, Ulloa-Aguirre A., Dias J.A. Gonadotropin Hormones and their Receptors. En: Yen and Jaffe´s Reproductive Endocrinology. Strauss JF, Barbieri RL, 9th. Edición, Elsevier, 2023, en prensa.
  2. Ulloa-Aguirre A, Janovick JA, Zariñán T, Hanyaloglu AC. Intracellular trafficking of G protein-coupled receptors to the plasma membrane in health and disease. In: Cellular Endocrinology in Health and Disease, 2nd Edition. Ulloa-Aguirre A and Tao Y.-X. (Eds), Academic Press-Elsevier, pp.3785-401, 2021.
  3. Ulloa-Aguirre A, Hanyaloglu AC, Zariñán T, Janovick JA. Protein homeostasis and regulation of intracellular trafficking of G protein-coupled receptors. En: Pey, AL (Ed), Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Elsevier Inc., pp. 247-277, 2020.
  4. Janovick JA, Ulloa-Aguirre A. Cellular high-throughput screening. En: Protein Homeostasis Diseases, Pey A. (ed.), 2020, pp. 344-358, Elsevier Inc./Academic Press, USA.
  5. Ulloa-Aguirre A, Janovick JA, Zariñán T, Hanyaloglu AC. Intracellular trafficking of G protein-coupled receptors to the plasma membrane in health and disease. In: Cellular Endocrinology in Health and Disease, 2nd Edition. Ulloa-Aguirre A and Tao Y.-X. (Eds), Academic Press-Elsevier, pp.3785-401.
  6. Ulloa-Aguirre A., Zariñán T, Lira-Albarrán S. Mutation of Gonadotropin-Releasing Hormone Receptor Gene. In: Reference Module in Biomedical Sciences, Huhtaniemi I and Martini L, eds, Elsevier, 2018, ISBN 9780128012383, https://doi.org/10.1016/B978-0-12-801238-3.04015-0.
  7. Ulloa-Aguirre A, Zariñán T, Gutiérrez-Sagal R, Dias JA. Intracellular trafficking of gonadotropin receptors in health and disease. In: Ulloa-Aguirre A, Tao Y-X. (Eds) Targetting Trafficking in Drug Development. Handbook of Experimental Pharmacology, Springer, Verlag, Germany, pp, 1-39. DOI 10-1007/164_2017_49, 2018. ISBN 978-3-319-74163-5.
  8. Narayan P, Ulloa-Aguirre A, Dias JA. Gonadotropin Hormones and their Receptors. En: Yen and Jaffe´s Reproductive Endocrinology. Strauss JF, Barbieri RL, 8a. Edición, Elsevier, 2018, , ISBN: 978-0-323-47912-7, 2018, pp. 25-57.
  9. Jenees J, Ulloa-Aguirre A, Janovick JA, Conn, PM. The gonadotropin-releasing hormone and its receptor. En: Pfaff DW y Joëls M. Hormones, Brain and Behavior 3rd edition, Vol. 3, Oxford: Academic Press; 2017. pp. 363-378.
  10. Ulloa-Aguirre A, Dias JA, Bousfield G. Gonadotropins. En: Endocrinology of the Testis and Male Reproduction-Handbook of Endocrinology-, Simoni M, Huhtaniemi I, Editores. Springer-Verlag GmbH, Germany, 2017. DOI 10.1007/978-3-319-29456-8_3-1.
  11. Ulloa-Aguirre A, Lira-Albarrán S. Clinical Aplication of Gonadotropins in the Male. En: Progress in Molecular Biology and Translational Science, Vol. 143, Gonadotropins from the bench side to bedside. Kumar TR, Editor. Conn, P.M., series Editor. Elsevier Inc, ISSN 1877-1173. pp.121-174, 2016.
  12. Ulloa-Aguirre A, Janovick JA, Conn PM, Lira-Albarrán S. Mutation of Gonadotropin-Releasing Hormone Receptor Gene. Reference Module in Biomedical Sciences. Elsevier, 2015.

Edición de libros

  1. Ulloa-Aguirre A and Tao Y.-X. (Eds). Cellular Endocrinology in Health and Disease, 2nd Edition. , Academic Press-Elsevier, pp.3785-401, 2021. ISBN 978-0-12-819801-9. Número de capítulos, 21. Autores extreanjeros 18; nacionales, 3.
  2. Ulloa-Aguirre A, Tao Y-X Eds. Targetting Trafficking in Drug Development. Handbook of Experimental Pharmacology, Springer, Verlag, Germany, 2018. ISSN 0171-2004; ISBN 978-3-319-74164-2. Número de capítulos, 15. Autores extranjeros, 15; nacionales, 1.
  3. Dorantes-Cuellar A, Martínez-Sibaja C, Ulloa-Aguirre A. (Editores): Endocrinología Clínica de Dorantes y Martínez. Sociedad Mexicana de Nutrición y Endocrinología A.C. El Manual Moderno, México. ISBN 978-607-448-555--4.

Patentes

  1. “Uso de la Buserelina para el tratamient de cáncer de mama”. Patente MX 358574B. Clasificación CIP: A61K 38/09 (2006.01), A61P 5/06; clasificación CPC: A61K 38/09 (2016.08).
  1. Ulloa-Aguirre, A., Zariñán, T., Gutiérrez-Sagal, R., & Tao, Y. (2022). Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.934685
  2. Flores-Ramírez, I., Rivas-Torres, M. Á., Rodríguez-Dorantes, M., Gutiérrez-Sagal, R., Baranda-Ávila, N., & Langley, E. (2021). Oncogenic role of PinX1 in prostate cancer cells through androgen receptor dependent and independent mechanisms. The Journal of Steroid Biochemistry and Molecular Biology, 210, 105858. https://doi.org/10.1016/j.jsbmb.2021.105858
  3. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab. ,2021, 106(2):e534-e550.
  4. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  5. Ulloa-Aguirre A, Zariñán T, Jardón-Valadez E, Gutiérrez-Sagal R, Dias JA. Structure-function relationships of the follicle-stimulating hormone receptor. Frontiers in Endocrinology 9:707 (1-17), 2018.
  6. García-Jiménez, G., Zariñán, T., Rodríguez-Valentín, R., Mejía-Domínguez, N.R., Gutiérrez-Sagal, R., Hernández-Montes, G., Tovar, A., Arechavaleta-Velasco, F., Canto, I.P., Granados, J., Pellicer, A., Ulloa-Aguirre, A. (2018). Frequency of the T307A, N680S, and 29G> A Single Nucleotide Polymorphisms in the Follicle Stimulating Hormone Receptor in Mexican subjects of Hispanic Ancestry. Reproductive Biology and Endocrinology, 16(1) https://doi.org/10.1186/s12958-018-0420-4.
  7. Enriquez J, Velázquez-Cruz R, Parra Torres A, Gutiérrez-Sagal R y Larrea F. The anti-estrogenic activity of indole-3-carbinol in neonatal rat osteoblasts is associated with the estrogen receptor antagonist 2-hydroxyestradiol. J. Endocrinol. Invest. June 2016.

Contribuciones en libros, capítulos y monografías

  1. Ulloa-Aguirre A, Zariñán T, Gutiérrez-Sagal R, Dias JA. Intracellular trafficking of gonadotropin receptors in health and disease. In: Ulloa-Aguirre A, Tao Y-X. (Eds) Targetting Trafficking in Drug Development. Handbook of Experimental Pharmacology, Springer, Verlag, Germany, pp, 1-39. DOI 10-1007/164_2017_49, 2018. ISBN 978-3-319-74163-5.
  1. Cruz-Huerta, E., Zariñán, T., Enríquez, J., Ulloa-Aguirre, A., & Gutiérrez-Sagal, R. (2024). Estrogen regulated transcription of the non-estrogen-regulated hamster uteroglobin gene in MCF-7 cells. General and Comparative Endocrinology, 347, 114424. https://doi.org/10.1016/j.ygcen.2023.114424
  2. Murillo-de-Ozores, A. R., Carbajal-Contreras, H., Magaña-Ávila, G. R., Valdés, R., Grajeda-Medina, L. I., Vázquez, N., Zariñán, T., López-Saavedra, A., Sharma, A., Lin, D., Wang, W., Delpire, E., Ellison, D. H., Gamba, G., & Castañeda-Bueno, M. (2022). Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia. Kidney International, 102(5), 1030-1041. https://doi.org/10.1016/j.kint.2022.06.027
  3. Ulloa-Aguirre, A., Zariñán, T., Gutiérrez-Sagal, R., & Tao, Y. (2022). Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.934685
  4. Murillo-de-Ozores AR, Carbajal-Contreras H, Magaña-Ávila GR, Valdés R, Grajeda-Medina LI, Vázquez N, Zariñán T, López-Saavedra A, Sharma A, Lin DH, Wang WH, Delpire E, Ellison DH, Gamba G, Castañeda-Bueno M. Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia [published online ahead of print, 2022 Jul 21]. Kidney Int. 2022; S0085-2538(22)00542-7. doi:10.1016/j.kint.2022.06.027.
  5. Ulloa-Aguirre A, Zariñán T, Jardón-Valadez E. Misfolded G Protein-Coupled Receptors and Endocrine Disease. Molecular Mechanisms and Therapeutic Prospects. Int J Mol Sci. 2021 Nov 15;22(22):12329. doi: 10.3390/ijms222212329. PMID: 34830210; PMCID: PMC8622668.
  6. Olmos-Ortiz A, Olivares-Huerta A, García-Quiroz J, Zariñán T, Chavira R, Zaga-Clavellina V, Avila E, Halhali A, Durand M, Larrea F, Díaz L. Placentas associated with female neonates from pregnancies complicated by urinary tract infections have higher cAMP content and cytokines expression than males. Am J Reprod Immunol. 2021;86(3):e13434. doi:10.1111/aji.13434
  7. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab. ,2021, 106(2):e534-e550.
  8. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  9. Ulloa-Aguirre A, Zariñán T, Jardón-Valadez E, Gutiérrez-Sagal R, Dias JA. Structure-function relationships of the follicle-stimulating hormone receptor. Frontiers in Endocrinology 9:707 (1-17), 2018.
  10. García-Jiménez, G., Zariñán, T., Rodríguez-Valentín, R., Mejía-Domínguez, N.R., Gutiérrez-Sagal, R., Hernández-Montes, G., Tovar, A., Arechavaleta-Velasco, F., Canto, I.P., Granados, J., Pellicer, A., Ulloa-Aguirre, A. (2018). Frequency of the T307A, N680S, and 29G> A Single Nucleotide Polymorphisms in the Follicle Stimulating Hormone Receptor in Mexican subjects of Hispanic Ancestry. Reproductive Biology and Endocrinology, 16(1) https://doi.org/10.1186/s12958-018-0420-4.
  11. Melo-Nava B, Casas-González P, Pérez-Solís M, Castillo-Badillo J, Maravillas-Montero JL, Jardón-Valadez E, Zariñán T, Aguilar-Rojas A, Gallay N, Reiter E, Ulloa-Aguirre A. Role of cysteine residues in the carboxyl-terminus of the follicle-stimulating hormone receptor in intracellular traffic and postendocytic processing. Frontiers in Cell and Developmental Biology, 4:76, 2016.
  12. Ulloa-Aguirre A, Zariñán T. The follitropin receptor. Matching structure and function. Molecular Pharmacology, 90:596-608, 2016.
  13. Ulloa-Aguirre A, Zariñán T, Conn PM. Pharmacoperones: Targeting therapeutics toward diseases caused by protein misfolding. Rev Invest Clin -Clinical and Translational Investigation-, 67(1):15-9, 2015.

Contribuciones en libros, capítulos y monografías

  1. Ulloa-Aguirre A, Janovick JA, Zariñán T, Hanyaloglu AC. Intracellular trafficking of G protein-coupled receptors to the plasma membrane in health and disease. In: Cellular Endocrinology in Health and Disease, 2nd Edition. Ulloa-Aguirre A and Tao Y.-X. (Eds), Academic Press-Elsevier, pp.3785-401, 2021.
  2. Ulloa-Aguirre A, Hanyaloglu AC, Zariñán T, Janovick JA. Protein homeostasis and regulation of intracellular trafficking of G protein-coupled receptors. En: Pey, AL (Ed), Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Elsevier Inc., pp. 247-277, 2020.
  3. Ulloa-Aguirre A, Janovick JA, Zariñán T, Hanyaloglu AC. Intracellular trafficking of G protein-coupled receptors to the plasma membrane in health and disease. In: Cellular Endocrinology in Health and Disease, 2nd Edition. Ulloa-Aguirre A and Tao Y.-X. (Eds), Academic Press-Elsevier, pp.3785-401.
  4. Ulloa-Aguirre A., Zariñán T, Lira-Albarrán S. Mutation of Gonadotropin-Releasing Hormone Receptor Gene. In: Reference Module in Biomedical Sciences, Huhtaniemi I and Martini L, eds, Elsevier, 2018, ISBN 9780128012383, https://doi.org/10.1016/B978-0-12-801238-3.04015-0.
  5. Ulloa-Aguirre A, Zariñán T, Gutiérrez-Sagal R, Dias JA. Intracellular trafficking of gonadotropin receptors in health and disease. In: Ulloa-Aguirre A, Tao Y-X. (Eds) Targetting Trafficking in Drug Development. Handbook of Experimental Pharmacology, Springer, Verlag, Germany, pp, 1-39. DOI 10-1007/164_2017_49, 2018. ISBN 978-3-319-74163-5.

º Citometría de Flujo

  1. León-Ortíz, P., Rivera-Chávez, L. F., Torres-Ruíz, J., Reyes-Madrigal, F., Carrillo-Vázquez, D. A., Moncada-Habib, T., Cassiano-Quezada, F., Cadenhead, K. S., Gómez-Martín, D., & De La Fuente-Sandoval, C. (2023). Systemic inflammation and cortical neurochemistry in never-medicated first episode-psychosis individuals. Brain, Behavior, and Immunity, 111, 270-276. https://doi.org/10.1016/j.bbi.2023.05.001
  2. Torres-Ruíz, J., Alcalá-Carmona, B., Alejandre-Aguilar, R., & Gómez-Martín, D. (2023). Inflammatory myopathies and beyond: The dual role of neutrophils in muscle damage and regeneration. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1113214
  3. Madera-Salcedo, I.K., Ramírez-Sánchez, A.L., Rodríguez-Rodríguez, N., García-Quintero, R., Rubio, R.M., Morales-Montes de Oca, G., Dávalos, E., Cuervo, R., Furuzawa-Carballeda, J., Alcocer-Varela, J., Gómez-Martín, D., González-Yáñez, M., de la Cruz, A., Albarrán-Godínez, A., Suárez-Rojas, G., Romero-Díaz, J., Uribe-Uribe, N.O., Alarcón-Riquelme, M., Furlan-Magaril, M., Mejía-Vilet, J.M., Crispín, J.C. and Rosetti, F. (2023), Down-Regulation-Resistant STAT4 Risk Haplotype Contributes to Lupus Nephritis Through CD4+ T Cell Interferon-γ Production. rthritis RheumatolA, 75: 961-972. https://doi.org/10.1002/art.42435
  4. Romero-Ramírez, S., Sosa-Hernández, V. A., Cervantes-Díaz, R., Carrillo-Vázquez, D. A., Meza-Sánchez, D. E., Núñez-Álvarez, C. A., Torres-Ruíz, J., Gómez-Martín, D., & Maravillas-Montero, J. L. (2023). Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1080154
  5. Jiram Torres-Ruiz, Abdiel Absalón-Aguilar, Juan Alberto Reyes-Islas, Fabiola Cassiano-Quezada, Nancy R Mejía-Domínguez, Alfredo Pérez-Fragoso, José Luis Maravillas-Montero, Carlos Núñez-Álvarez, Guillermo Juárez-Vega, Alejandro Culebro-Bermejo, Diana Gómez-Martín, Peripheral expansion of myeloid-derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies, Rheumatology, Volume 62, Issue 2, February 2023, Pages 775-784, https://doi.org/10.1093/rheumatology/keac374
  6. Torres-Ruíz, J., Rull-Gabayet, M.,Mejía-Domínguez, N. R. , Carrillo-Vázquez, D. A., Reyes-Islas, J. A., Cassiano-Quezada, F., Cuéllar-Rodríguez, J., Sierra-Madero, J., Sánchez, J. L. G. M., Serrano-García, J. S., González, A. O., Juárez-Vega, G., Tapia-Rodríguez, M., & Gómez-Martín, D. (2023). Disease activity is associated with changes in the innate immune function in patients with systemic lupus erythematosus. Clinical Rheumatology. https://doi.org/10.1007/s10067-023-06810-6
  7. Jiram Torres-Ruiz, Julieta Lomelín-Gascón, Jaquelin Lira Luna, Ana Sofia Vargas- Castro, Alfredo Pérez-Fragoso, Miroslava Nuñez-Aguirre, Beatriz Alcalá-Carmona, Abdiel Absalón-Aguilar, Jennifer T. Balderas-Miranda, José Luis Maravillas-Montero, Nancy R. Mejía-Domínguez, Carlos Núñez-Álvarez, Luis Llorente, Sandra Romero-Ramírez, Victor Andrés Sosa-Hernández, Rodrigo Cervantes-Díaz, Guillermo Juárez-Vega, David Meza-Sánchez, Marina Rull-Gabayet, Luis Alberto Martínez-Juárez, Linda Morales, Lizeth Naomi López-López, José Adrián Negrete-Trujillo, Jorge Abelardo Falcón-Lezama, Rafael Ricardo Valdez-Vázquez, Héctor Gallardo-Rincón, Roberto Tapia-Conyer & Diana Gómez-Martín (2023) Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study, Infectious Diseases, 55:4, 243-254, DOI: 10.1080/23744235.2022.2158217
  8. Raul Fernando Reyes, Jiram Torres-Ruiz, Diana Gómez-Martin, José Luis Maravillas-Montero; Double Negative B cells are decreased in patients with Idiopathic Inflammatory Myopathies. J Immunol 1 May 2023; 210 (1_Supplement): 247.11. https://doi.org/10.4049/jimmunol.210.Supp.247.11
  9. Torres-Ruiz J, Lomelín-Gascón J, Vargas-Castro AS, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Rull-Gabayet M, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez DE, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study. Front Immunol. 2022 Aug 15;13:943563. doi: 10.3389/fimmu.2022.943563.
  10. Sosa-Hernández Víctor A., Romero-Ramírez Sandra, Cervantes-Díaz Rodrigo, Carrillo-Vázquez Daniel A., Navarro-Hernandez Itze C., Whittall-García Laura P., Absalón-Aguilar Abdiel, Vargas-Castro Ana S., Reyes-Huerta Raúl F., Juárez-Vega Guillermo, Meza-Sánchez David E., Ortiz-Navarrete Vianney, Torres-Ruiz Jiram, Mejía-Domínguez N.R., Gómez-Martín Diana, Maravillas-Montero José L. (2022) CD11c+ T-bet+ CD21hi B Cells Are Negatively Associated With Renal Impairment in Systemic Lupus Erythematosus and Act as a Marker for Nephritis Remission. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.892241
  11. Cervantes-Díaz R, Sosa-Hernández VA, Romero-Ramírez S, Torres-Ruiz J, Pérez-Fragoso A, Meza-Sánchez DE, Gómez-Martín D, Maravillas-Montero JL. Circulating B10 regulatory cells are decreased in severe and critical COVID-19. J Leukoc Biol. 2022 Aug;112(2):333-337. doi: 10.1002/JLB.5COVCRA0721-387RR.
  12. Cervantes-Díaz R, Sosa-Hernández VA, Torres-Ruíz J, Romero-Ramírez S, Cañez-Hernández M, Pérez-Fragoso A, Páez-Franco JC, Meza-Sánchez DE, Pescador-Rojas M, Sosa-Hernández VA, Gómez-Martín D, Maravillas-Montero JL. Severity of SARS-CoV-2 infection is linked to double-negative (CD27- IgD-) B cell subset numbers. Inflamm Res. 2022 Jan;71(1):131-140. doi: 10.1007/s00011-021-01525-3. Epub 2021 Nov 30.
  13. Torres-Ruiz J, Lomelín-Gascón J, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez D, Rull-Gabayet M, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients. Clin Transl Med. 2021 Nov;11(11):e623.
  14. García-Cordero J, Mendoza-Ramírez J, Fernández-Benavides D, Roa-Velazquez D, Filisola-Villaseñor J, Martínez-Frías SP, Sanchez-Salguero ES, Miguel-Rodríguez CE, Maravillas Montero JL, Torres-Ruiz JJ, Gómez-Martín D, Argumedo LS, Morales-Ríos E, Alvarado-Orozco JM, Cedillo-Barrón L. Recombinant Protein Expression and Purification of N, S1, and RBD of SARS-CoV-2 from Mammalian Cells and Their Potential Applications. Diagnostics (Basel). 2021 Sep 30;11(10):1808.
  15. Torres-Ruiz J, Absalón-Aguilar A, Nuñez-Aguirre M, Pérez-Fragoso A, Carrillo-Vázquez DA, Maravillas-Montero JL, Mejía-Domínguez NR, Llorente L, Alcalá-Carmona B, Lira-Luna J, Núñez-Álvarez C, Juárez-Vega G, Meza-Sánchez D, Hernández-Gilsoul T, Tapia-Rodríguez M, Gómez-Martín D. Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity. Cells. 2021 Sep 26;10(10):2545.
  16. Soria-Castro R, Meneses-Preza YG, Rodríguez-López GM, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Pérez-Fragoso A, Torres-Ruíz JJ, Gómez-Martín D, Campillo-Navarro M, Álvarez-Jiménez VD, Pérez-Tapia SM, Chávez-Blanco AD, Estrada-Parra S, Maravillas-Montero JL, Chacón-Salinas R. Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin. J Leukoc Biol. 2021 Sep;110(3):425-431.
  17. Torres-Ruiz J, Pérez-Fragoso A, Maravillas-Montero JL, Llorente L, Mejía-Domínguez NR, Páez-Franco JC, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Absalón-Aguilar A, Nuñez-Aguirre M, Juárez-Vega G, Meza-Sánchez D, Kleinberg-Bid A, Hernández-Gilsoul T, Ponce-de-León A, Gómez-Martín D. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021 Sep 8;12:689966.
  18. Torres-Ruiz J, Carrillo-Vazquez DA, Leal-Alanis A, Zentella-Dehesa A, Tapia-Rodriguez M, Maravillas-Montero JL, Nunez-Alvarez CA, Carazo-Vargas ER, Romero-Hernandez I, Juarez-Vega G, Alcocer-Varela J, Gomez-Martin D. Low-Density Granulocytes and Neutrophil Extracellular Traps as Biomarkers of Disease Activity in Adult Inflammatory Myopathies. J Clin Rheumatol. 2021 Jul 26. doi: 10.1097/RHU.0000000000001772. Online ahead of print.
  19. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  20. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.
  21. Torres-Ruiz J, Carrillo-Vazquez DA, Padilla-Ortiz DM, Vazquez-Rodriguez R, Nuñez-Alvarez C, Juarez-Vega G, Gomez-Martin D. TLR expression in peripheral monocyte subsets of patients with idiopathic inflammatory myopathies: association with clinical and immunological features. J Transl Med. 2020, 12;18(1):125.
  22. Cruz-González DJ, Gómez-Martin D, Baranda L, Abud-Mendoza C, Alcocer-Varela J, González-Amaro R, Monsiváis-Urenda AE. Analysis of the Regulatory Function of NK Cells from Patients with Systemic Lupus Erythematosus. Clin Exp Immunol. 2018 Mar;191(3):288-300.
  23. Romo-Tena J, Rajme-López S, Aparicio-Vera L, Alcocer-Varela J, Gómez-Martín D. Lys63-Polyubiquitination by the E3 Ligase Casitas B-Lineage Lymphoma-b (Cbl-b) Modulates Peripheral Regulatory T Cell Tolerance in Patients with Systemic Lupus Erythematosus. Clin Exp Immunol. 2018 Jan;191(1):42-49.
  24. León-Rodríguez E, Rivera-Franco MM, Gómez-Martín D, Romo-Tena J, Juárez-Vega G, Merayo-Chalico J, Alcocer-Varela J. Differential T cell subsets and cytokine profile between steady-state and G-CSF-primed bone marrow and its association with graft-versus-host disease. Leuk Res. 2017 Nov 1;63:47-52.
  25. Merayo-Chalico J, Barrera-Vargas A, Juárez-Vega G, Alcocer-Varela J, Arauz A, Gómez-Martín. Differential serum cytokine profile in patients with systemic lupus erythematosus and posterior reversible encephalopathy syndrome. Clin Exp Immunol. 2017 Dec 22.
  26. Gómez-Martín D, Galindo-Feria AS, Barrera-Vargas A, Merayo-Chalico J, Juárez-Vega G, Torres-Ruiz J, Alcocer-Varela J. Ro52/TRIM21 deficient expression and function in different subsets of peripheral blood mononuclear cells is associated with a pro-inflammatory cytokine response in patients with idiopathic inflammatory myopathies. Clin Exp Immunol. 2016, Dec 09.

Previas

  1. Merayo-Chalico J, Apodaca E, Barrera-Vargas A, Alcocer-Varela J, Colunga-Pedraza I, González-Patiño A, Arauz A, Abud-Mendoza C, Martínez-Martínez M, Gómez-Martín D. Clinical outcomes and risk factors for posterior reversible encephalopathy syndrome in systemic lupus erythematosus: a multicentric case-control study. J Neurol Neurosurg Psychiatry. 2016 Mar; 87(3):287-94.
  2. Espinosa-Ortega F, Gómez-Martin D, Santana-De Anda K, Romo-Tena J, Villaseñor-Ovies P, Alcocer-Varela J.Quantitative T cell subsets profile in peripheral blood from patients with idiopathic inflammatory myopathies: Tilting the balance towards pro-inflammatory and pro-apoptotic subsets. Clin Exp Immunol. 2015. Mar; 179 (3): 520-8.
  3. Santana-de-Anda K, Gómez-Martín D, Monsiváis-Urenda AE, Salgado-Bustamante M, González-Amaro R, Alcocer-Varela J. Interferon regulatory factor 3 as key element of the interferon signature in plasmacytoid dendritic cells from Systemic Lupus Erythematosus patients: Novel genetic associations in Mexican-mestizo population. Clin Exp Immunol. 2014. Dec; 178 (3): 428-37.
  4. Monsiváis-Urenda A, Gómez-Martín D, Santana-de-Anda K, Cruz-Martínez J, Alcocer-Varela J, González-Amaro R. Defective expression and function of the ILT2/CD85j regulatory receptor in dendritic cells from patients with systemic lupus erythematosus. Hum Immunol. 2013 Sep; 74 (9):1088-96.
  5. Gómez- Martín D, Ibarra-Sánchez M, Romo-Tena J, Cruz-Ruíz J, Esparza-López J, Galindo-Campos M, Díaz-Zamudio M, Alcocer-Varela J. Casitas B-lineage-lymphoma-b is a key regulator of peripheral tolerance in systemic lupus erythematosus. Arthritis Rheum. 2013 Apr 65(4): 1032-42.
  1. Torres-Ruíz, J., Rull-Gabayet, M., MejíaDomínguez, N. R., Carrillo-Vázquez, D. A., Reyes-Islas, J. A., Cassiano-Quezada, F., Cuéllar-Rodríguez, J., Sierra-Madero, J., Sánchez, J. L. G. M., Serrano-García, J. S., González, A. O., Juárez-Vega, G., Tapia-Rodríguez, M., & Gómez-Martín, D. (2023). Disease activity is associated with changes in the innate immune function in patients with systemic lupus erythematosus. Clinical Rheumatology. https://doi.org/10.1007/s10067-023-06810-6
  2. Jiram Torres-Ruiz, Julieta Lomelín-Gascón, Jaquelin Lira Luna, Ana Sofia Vargas- Castro, Alfredo Pérez-Fragoso, Miroslava Nuñez-Aguirre, Beatriz Alcalá-Carmona, Abdiel Absalón-Aguilar, Jennifer T. Balderas-Miranda, José Luis Maravillas-Montero, Nancy R. Mejía-Domínguez, Carlos Núñez-Álvarez, Luis Llorente, Sandra Romero-Ramírez, Victor Andrés Sosa-Hernández, Rodrigo Cervantes-Díaz, Guillermo Juárez-Vega, David Meza-Sánchez, Marina Rull-Gabayet, Luis Alberto Martínez-Juárez, Linda Morales, Lizeth Naomi López-López, José Adrián Negrete-Trujillo, Jorge Abelardo Falcón-Lezama, Rafael Ricardo Valdez-Vázquez, Héctor Gallardo-Rincón, Roberto Tapia-Conyer & Diana Gómez-Martín (2023) Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study, Infectious Diseases, 55:4, 243-254, DOI: 10.1080/23744235.2022.2158217
  3. Jiram Torres-Ruiz, Abdiel Absalón-Aguilar, Juan Alberto Reyes-Islas, Fabiola Cassiano-Quezada, Nancy R Mejía-Domínguez, Alfredo Pérez-Fragoso, José Luis Maravillas-Montero, Carlos Núñez-Álvarez, Guillermo Juárez-Vega, Alejandro Culebro-Bermejo, Diana Gómez-Martín, Peripheral expansion of myeloid-derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies, Rheumatology, Volume 62, Issue 2, February 2023, Pages 775-784, https://doi.org/10.1093/rheumatology/keac374
  4. Torres-Ruiz j, Absalón-Aguilar A, Reyes-Islas J, Pérez-Fragoso A, Mejía-Domínguez N, Alfaro-Goldaracena A, Alcalá-Carmona B, Juárez-Vega G, Cassiano-Quezada F, Gómez-Martín D. Analysis of the Association Between the Atrophic Factors Tripartite Motif Containing (TRIM) 63 and Atrogin-1 and the Clinical and Inflammatory Features of Patients with Idiopathic Inflammatory Myopathies [abstract]. Arthritis Rheumatol. 2022; 74 (suppl 9).
  5. Absalón-Aguilar, A., Rull-Gabayet, M., Pérez-Fragoso, A., Mejía-Domínguez, N. R., Núñez-Álvarez, C. A., Kershenobich-Stalnikowitz, D., Sifuentes-Osornio, J., Ponce-De-León, A., González-Lara, F., Martín-Nares, E., Montesinos-Ramírez, S., Ramírez-Alemón, M., Ramírez-Rangel, P., Márquez, M. F., Plata-Corona, J. C., Juárez-Vega, G., Gómez-Martín, D., & Torres-Ruíz, J. (2021). Colchicine Is Safe Though Ineffective in the Treatment of Severe COVID-19: a Randomized Clinical Trial (COLCHIVID). Journal of General Internal Medicine, 37(1), 4–14. https://doi.org/10.1007/s11606-021-07203-8
  6. Torres-Ruiz J, Lomelín-Gascón J, Vargas-Castro AS, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Rull-Gabayet M, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez DE, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study. Front Immunol. 2022 Aug 15;13:943563. doi: 10.3389/fimmu.2022.943563.
  7. Sosa-Hernández Víctor A., Romero-Ramírez Sandra, Cervantes-Díaz Rodrigo, Carrillo-Vázquez Daniel A., Navarro-Hernandez Itze C., Whittall-García Laura P., Absalón-Aguilar Abdiel, Vargas-Castro Ana S., Reyes-Huerta Raúl F., Juárez-Vega Guillermo, Meza-Sánchez David E., Ortiz-Navarrete Vianney, Torres-Ruiz Jiram, Mejía-Domínguez N.R., Gómez-Martín Diana, Maravillas-Montero José L. (2022) CD11c+ T-bet+ CD21hi B Cells Are Negatively Associated With Renal Impairment in Systemic Lupus Erythematosus and Act as a Marker for Nephritis Remission. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.892241
  8. Torres-Ruiz J, Lomelín-Gascón J, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez D, Rull-Gabayet M, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients. Clin Transl Med. 2021 Nov;11(11):e623.
  9. Torres-Ruiz J, Pérez-Fragoso A, Maravillas-Montero JL, Llorente L, Mejía-Domínguez NR, Páez-Franco JC, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Absalón-Aguilar A, Nuñez-Aguirre M, Juárez-Vega G, Meza-Sánchez D, Kleinberg-Bid A, Hernández-Gilsoul T, Ponce-de-León A, Gómez-Martín D. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021 Sep 8;12:689966.
  10. Torres-Ruiz J, Carrillo-Vazquez DA, Leal-Alanis A, Zentella-Dehesa A, Tapia-Rodriguez M, Maravillas-Montero JL, Nunez-Alvarez CA, Carazo-Vargas ER, Romero-Hernandez I, Juarez-Vega G, Alcocer-Varela J, Gomez-Martin D. Low-Density Granulocytes and Neutrophil Extracellular Traps as Biomarkers of Disease Activity in Adult Inflammatory Myopathies. J Clin Rheumatol. 2021 Jul 26. doi: 10.1097/RHU.0000000000001772. Online ahead of print.
  11. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.
  12. Torres-Ruiz J, Carrillo-Vazquez DA, Padilla-Ortiz DM, Vazquez-Rodriguez R, Nuñez-Alvarez C, Juarez-Vega G, Gomez-Martin D. TLR expression in peripheral monocyte subsets of patients with idiopathic inflammatory myopathies: association with clinical and immunological features. J Transl Med. 2020, 12;18(1):125.
  13. Valente-Acosta B, Flores-García M, González-Zárate G, Gerson-Cwilich R, Maldonado-Méndez M, Juárez-Vega G, Anglés-Cano E, Peña-Díaz A. Fibrinolytic Activity of Circulating Microvesicles Is Associated with Progression of Breast Cancer. Tohoku J Exp Med. 2020, 250(2):121-128
  14. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  15. Torres-Ruiz J, Mejía-Domínguez NR, Zentella-Dehesa A, Ponce-de-León A, Morales-Padilla SR, Vázquez-Rodríguez R, Alvarado-Lara MR, Reyna-de-la-Garza RA, Tapia-Rodríguez M, Juárez-Vega G, Merayo-Chalico J, Barrera-Vargas A, Alcocer-Varela JC, Gómez-Martín D. The Systemic Lupus Erythematosus Infection Predictive Index (LIPI): A Clinical-Immunological Tool to Predict Infections in Lupus Patients. Front Immunol. 9:3144. 2019 Jan 14.
  16. Merayo-Chalico J, Barrera-Vargas A, Juárez-Vega G, Alcocer-Varela J, Arauz A, Gómez-Martín D. Differential serum cytokine profile in patients with systemic lupus erythematosus and posterior reversible encephalopathy syndrome. Clin Exp Immunol. 192(2):165-170. 2018 Jan 16.
  17. Juárez-Vega G, Rangel-Ramírez V, Monsiváis-Urenda A, Niño-Moreno P, Garcia-Sepúlveda C, Noyola DE, González-Amaro R. Comparative analysis of NK cell receptor repertoire in adults and very elderly subjects with cytomegalovirus infection. Hum Immunol. 78(3):274-280. 2017 Jan 16.
  18. León-Rodríguez E, Rivera-Franco MM, Gómez-Martín D, Romo-Tena J, Juárez-Vega G, Merayo-Chalico J, Alcocer-Varela J. Differential T cell subsets and cytokine profile between steady-state and G-CSF-primed bone marrow and its association with graft-versus-host disease. Leuk Res. 2017 Nov 1;63:47-52.
  19. Merayo-Chalico J, Barrera-Vargas A, Juárez-Vega G, Alcocer-Varela J, Arauz A, Gómez-Martín. Differential serum cytokine profile in patients with systemic lupus erythematosus and posterior reversible encephalopathy syndrome. Clin Exp Immunol. 2017 Dec 22.
  20. Gómez-Martín D, Galindo-Feria AS, Barrera-Vargas A, Merayo-Chalico J, Juárez-Vega G, Torres-Ruiz J, Alcocer-Varela J. Ro52/TRIM21 deficient expression and function in different subsets of peripheral blood mononuclear cells is associated with a pro-inflammatory cytokine response in patients with idiopathic inflammatory myopathies. Clin Exp Immunol. 2016, Dec 09.

º Metabolómica y Proteómica

  1. Pedro, N., Arroyo-Hernández, M., Sosa-Hernández, V. A., Romero-Nuñez, E., Maravillas-Montero, J. L., Orozco-Morales, M., Barrios-Bernal, P., Lucio-Lozada, J., Estrada, D. F., & Arrieta, O. (2023). EP03.03-09 Impact of Tyrosine Kinase Inhibitors on the Immune Response to SARS CoV2 Vaccination in Patients with Non Small Cell Lung Cancer. Journal of Thoracic Oncology, 18(11), S446. https://doi.org/10.1016/j.jtho.2023.09.815
  2. Hernández-Pedro, N., Arroyo-Hernández, M., Barrios-Bernal, P., Romero-Nuñez, E., Sosa-Hernández, V. A., Ávila-Ríos, S., Maravillas-Montero, J. L., Pérez-Padilla, R., Pérez, D., Rolfo, C., & Arrieta, Ó. (2023). Impact of Tyrosine Kinase Inhibitors on the Immune Response to SARS-CoV-2 Vaccination in Patients with Non-Small Cell Lung Cancer. Vaccines, 11(10), 1612. https://doi.org/10.3390/vaccines11101612
  3. Velázquez-Cervantes, M., Benítez-Zeferino, Y. R., Flores-Pliego, A., Helguera-Repetto, A. C., Meza-Sánchez, D. E., Maravillas-Montero, J. L., León-Reyes, G., Mancilla-Ramírez, J., Cerna-Cortés, J. F., Baeza-Ramírez, M. I., & León-Juárez, M. (2023). A review study of the participation of late domains in sorting and transport of viral factors to exosomes. Life, 13(9), 1842. https://doi.org/10.3390/life13091842
  4. Barragan-Galvez, J. C., López-Ortega, O., Hernandez-Flores, A., Rodriguez-Alvarez, A. A., Maravillas-Montero, J. L., & Ortíz-Navarrete, V. (2023). The constant domain of CRTAM is essential for high-affinity interaction with Nectin-like 2. Research Square. https://doi.org/10.21203/rs.3.rs-3143599/v1
  5. Raul Fernando Reyes, Jiram Torres-Ruiz, Diana Gómez-Martin, José Luis Maravillas-Montero; Double Negative B cells are decreased in patients with Idiopathic Inflammatory Myopathies. J Immunol 1 May 2023; 210 (1_Supplement): 247.11. https://doi.org/10.4049/jimmunol.210.Supp.247.11
  6. Torres-Ruíz, J., Lomelín-Gascón, J., Luna, J. L., Vargas-Castro, A. S., Pérez-Fragoso, A., Nuñez-Aguirre, M., Alcalá-Carmona, B., Absalón-Aguilar, A., Balderas-Miranda, J. T., Maravillas-Montero, J. L., Mejía-Domínguez, N. R., Núñez-Álvarez, C. A., Llórente, L., Romero-Ramírez, S., Sosa-Hernández, V. A., Cervantes-Díaz, R., Juárez-Vega, G., Meza-Sánchez, D. E., Rull-Gabayet, M., Gómez-Martín, D. (2023). Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study. Infectious Diseases, 55(4), 243-254. https://doi.org/10.1080/23744235.2022.2158217
  7. Romero-Ramírez, S., Sosa-Hernández, V. A., Cervantes-Díaz, R., Carrillo-Vázquez, D. A., Meza-Sánchez, D. E., Núñez-Álvarez, C. A., Torres-Ruíz, J., Gómez-Martín, D., & Maravillas-Montero, J. L. (2023). Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1080154
  8. Jiram Torres-Ruiz, Abdiel Absalón-Aguilar, Juan Alberto Reyes-Islas, Fabiola Cassiano-Quezada, Nancy R Mejía-Domínguez, Alfredo Pérez-Fragoso, José Luis Maravillas-Montero, Carlos Núñez-Álvarez, Guillermo Juárez-Vega, Alejandro Culebro-Bermejo, Diana Gómez-Martín, Peripheral expansion of myeloid-derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies, Rheumatology, Volume 62, Issue 2, February 2023, Pages 775-784, https://doi.org/10.1093/rheumatology/keac374
  9. Cedillo-Alcantar, D. F., Rodriguez-Moncayo, R., Maravillas-Montero, J. L., & García-Cordero, J. L. (2023). On-Chip Analysis of Protein Secretion from Single Cells Using Microbead Biosensors. ACS Sensors, 8(2), 655-664. https://doi.org/10.1021/acssensors.2c02148
  10. Pérez-Noriega, F. A., Salinas-Lara, C., Sánchez-Garibay, C., Torres-Ruíz, J. J., Maravillas-Montero, J. L., Castañón-Arreola, M., Hernández-Campos, M. E., Rodríguez-Balderas, C. A., Basurto-López, B. V., Peñafiel-Salgado, C., Espinosa-García, A. P., Choreño-Parra, J. A., Tena-Suck, M. L., Soto-Rojas, L. O., León-Marroquín, E. Y., Romero-López, J. P., & Castillejos-López, M. (2023). Mycobacterium tuberculosis Cell Wall Antigens Induce the Formation of Immune Complexes and the Development of Vasculitis in an Experimental Murine Model. International Journal of Molecular Sciences, 24(2), 1242. https://doi.org/10.3390/ijms24021242
  11. Maravillas-Montero, José L., & Reyes-Huerta, Raúl F.. (2022). Update on Novel Blood-Based Biomarkers for Lupus Nephritis Beyond Diagnostic Approaches. Revista de investigación clínica, 74(5), 227-231. Epub 18 de noviembre de 2022.https://doi.org/10.24875/ric.22000209
  12. Páez-Franco, J. C., Maravillas-Montero, J. L., Mejía-Domínguez, N. R., Torres-Ruíz, J., Tamez-Torres, K. M., Pérez-Fragoso, A., Germán-Acacio, J. M., Ponce-De-León, A., Gómez-Martín, D., & Ulloa-Aguirre, A. (2022). Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology. PLOS ONE, 17(9), e0274910. https://doi.org/10.1371/journal.pone.0274910
  13. Guadalupe Rivera-Torruco, Carolina A. Martínez-Mendiola, Tania Angeles-Floriano, Gustavo Alberto Jaimes-Ortega, José Luis Maravillas-Montero, Rodolfo García-Contreras, Yolanda González, Esmeralda Juárez, Porfirio Nava, Vianney Ortiz-Navarrete, Oscar Medina-Contreras, Paula Licona-Limón, Ricardo Valle-Rios, "Isthmin 1 is Expressed by Progenitor-Like Cells in the Lung: Phenotypical Analysis of Isthmin 1+ Hematopoietic Stem-Like Cells in Homeostasis and during Infection", Journal of Immunology Research, vol. 2022, Article ID 2909487, 13 pages, 2022. https://doi.org/10.1155/2022/2909487
  14. Torres-Ruiz J, Lomelín-Gascón J, Vargas-Castro AS, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Rull-Gabayet M, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez DE, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study. Front Immunol. 2022 Aug 15;13:943563. doi: 10.3389/fimmu.2022.943563.
  15. Sosa-Hernández Víctor A., Romero-Ramírez Sandra, Cervantes-Díaz Rodrigo, Carrillo-Vázquez Daniel A., Navarro-Hernandez Itze C., Whittall-García Laura P., Absalón-Aguilar Abdiel, Vargas-Castro Ana S., Reyes-Huerta Raúl F., Juárez-Vega Guillermo, Meza-Sánchez David E., Ortiz-Navarrete Vianney, Torres-Ruiz Jiram, Mejía-Domínguez N.R., Gómez-Martín Diana, Maravillas-Montero José L. (2022) CD11c+ T-bet+ CD21hi B Cells Are Negatively Associated With Renal Impairment in Systemic Lupus Erythematosus and Act as a Marker for Nephritis Remission. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.892241
  16. Cervantes-Díaz R, Sosa-Hernández VA, Romero-Ramírez S, Torres-Ruiz J, Pérez-Fragoso A, Meza-Sánchez DE, Gómez-Martín D, Maravillas-Montero JL. Circulating B10 regulatory cells are decreased in severe and critical COVID-19. J Leukoc Biol. 2022 Aug;112(2):333-337. doi: 10.1002/JLB.5COVCRA0721-387RR.
  17. Cervantes-Díaz R, Sosa-Hernández VA, Torres-Ruíz J, Romero-Ramírez S, Cañez-Hernández M, Pérez-Fragoso A, Páez-Franco JC, Meza-Sánchez DE, Pescador-Rojas M, Sosa-Hernández VA, Gómez-Martín D, Maravillas-Montero JL. Severity of SARS-CoV-2 infection is linked to double-negative (CD27- IgD-) B cell subset numbers. Inflamm Res. 2022 Jan;71(1):131-140.
  18. Gutierrez-Guerrero A, Mancilla-Herrera I, Maravillas-Montero JL, Martinez-Duncker I, Veillette A, Cruz-Munoz ME. SLAMF7 selectively favors degranulation to promote cytotoxicity in human NK cells. Eur J Immunol. 2022 Jan;52(1):62-74.
  19. Torres-Ruiz J, Lomelín-Gascón J, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez D, Rull-Gabayet M, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients. Clin Transl Med. 2021 Nov;11(11):e623.
  20. Torres-Ruiz J, Absalón-Aguilar A, Nuñez-Aguirre M, Pérez-Fragoso A, Carrillo-Vázquez DA, Maravillas-Montero JL, Mejía-Domínguez NR, Llorente L, Alcalá-Carmona B, Lira-Luna J, Núñez-Álvarez C, Juárez-Vega G, Meza-Sánchez D, Hernández-Gilsoul T, Tapia-Rodríguez M, Gómez-Martín D. Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity. Cells. 2021 Sep 26;10(10):2545.
  21. García-Cordero J, Mendoza-Ramírez J, Fernández-Benavides D, Roa-Velazquez D, Filisola-Villaseñor J, Martínez-Frías SP, Sanchez-Salguero ES, Miguel-Rodríguez CE, Maravillas Montero JL, Torres-Ruiz JJ, Gómez-Martín D, Argumedo LS, Morales-Ríos E, Alvarado-Orozco JM, Cedillo-Barrón L. Recombinant Protein Expression and Purification of N, S1, and RBD of SARS-CoV-2 from Mammalian Cells and Their Potential Applications. Diagnostics (Basel). 2021 Sep 30;11(10):1808.
  22. Torres-Ruiz J, Carrillo-Vazquez DA, Leal-Alanis A, Zentella-Dehesa A, Tapia-Rodriguez M, Maravillas-Montero JL, Nunez-Alvarez CA, Carazo-Vargas ER, Romero-Hernandez I, Juarez-Vega G, Alcocer-Varela J, Gomez-Martin D. Low-Density Granulocytes and Neutrophil Extracellular Traps as Biomarkers of Disease Activity in Adult Inflammatory Myopathies. J Clin Rheumatol. 2021 Jul 26. Online ahead of print.
  23. Torres-Ruiz J, Pérez-Fragoso A, Maravillas-Montero JL, Llorente L, Mejía-Domínguez NR, Páez-Franco JC, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Absalón-Aguilar A, Nuñez-Aguirre M, Juárez-Vega G, Meza-Sánchez D, Kleinberg-Bid A, Hernández-Gilsoul T, Ponce-de-León A, Gómez-Martín D. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021 Sep 8;12:689966. eCollection 2021.
  24. Soria-Castro R, Meneses-Preza YG, Rodríguez-López GM, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Pérez-Fragoso A, Torres-Ruíz JJ, Gómez-Martín D, Campillo-Navarro M, Álvarez-Jiménez VD, Pérez-Tapia SM, Chávez-Blanco AD, Estrada-Parra S, Maravillas-Montero JL, Chacón-Salinas R. Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin. J Leukoc Biol. 2021 Sep;110(3):425-431.
  25. Navarro-Hernandez IC, Acevedo-Ochoa E, Juárez-Vega G, Meza-Sánchez DE, Hernández-Hernández JM, Maravillas-Montero JL. Size Determination and Phenotypic Analysis of Urinary Extracellular Vesicles using Flow Cytometry. J Vis Exp. 2021 Apr 23;(170).
  26. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab. ,2021, 106(2):e534-e550.
  27. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  28. Aguilar-Valdés A., Noriega L-G., Tovar A.R., Ibarra-Sánchez M.J., Sosa-Hernández V.A., Maravillas-Montero J.L., Martínez-Aguilar J. SWATH-MS proteomics of PANC-1 and MIA PaCa-2 pancreatic cancer cells allows identification of drug targets alternative to MEK and PI3K inhibition, Biochem Biophys Res Commun, 552 (2021) 23-29.
  29. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.
  30. Garza-Reyes MG, Mora-Ruíz MD, Chávez-Sánchez L, Madrid-Miller A, Cabrera- Quintero AJ, Maravillas-Montero JL, Zentella-Dehesa A, Moreno-Ruíz L, Pastor- Salgado S, Ramírez-Arias E, Pérez-Velázquez N, Chávez-Rueda AK, Blanco- Favela F, Vazquez-Gonzalez WG, Contreras-Rodríguez A. Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction. Journal of Immunologic Research. 2020:5692829.
  31. García-Rivas G, Castillo EC, Gonzalez-Gil AM, Maravillas-Montero JL, Brunck M, Torres-Quintanilla A, Elizondo-Montemayor L, Torre-Amione G. The role of B cells in heart failure and implications for future immunomodulatory treatment strategies. ESC Heart Failure. 2020,7(4):1387-1399
  32. Barragan-Galvez JC, Gonzalez-Orozco M, Hernandez-Flores A, Maravillas-Montero JL, Chavez-Guerrero Y, Ortiz-Navarrete V. Prokaryotic Expression of the Immunoglobulin's Domains of CRTAM to Characterize a Monoclonal Antibody. Protein Journal. 2020, 39(3):224-231.
  33. Gomez Godinez V, Kabbara S, Sherman A, Wu T, Cohen S, Kong X, Maravillas-Montero JL, Shi Z, Preece D, Yokomori K, Berns MW.DNA damage induced during mitosis undergoes DNA repair synthesis. PLoS One. 2020, 15(4):e0227849
  34. Navarro-Hernandez IC, López-Ortega O, Acevedo-Ochoa E, Cervantes-Díaz R, Romero-Ramírez S, Sosa-Hernandez VA, Meza-Sánchez DE, Juárez-Vega G, Pérez-Martínez CA, Chávez-Munguía B, Galván-Hernández A, Antillón A, Ortega- Blake I, Santos-Argumedo L, Hernández-Hernández JM, Maravillas-Montero JL.Tetraspanin 33 (TSPAN33) Regulates Endocytosis and Migration of Human B Lymphocytes by Affecting the Tension of the Plasma Membrane. The FEBS Journal. 2020,287(16):3449-3471.
  35. Zariñán T, Butnev VY, Gutiérrez Sagal R, Maravillas-Montero JL, Martínez-Luis I, Mejía-Domínguez N, Juárez-Vega G, Bousfield GR, Ulloa-Aguirre A. In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity. Journal of the Endocrine Society, 2020, 4(5):1-23.
  36. Romero-Ramírez S, Navarro-Hernandez IC, Cervantes-Díaz R, Sosa-Hernández VA, Acevedo-Ochoa E, Kleinberg-Bild A, Valle-Rios R, Meza-Sánchez DE, Hernández-Hernández JM, Maravillas-Montero JL. Innate-like B cell subsets during immune responses: Beyond antibody production. Journal of Leukocyte Biology 105(5):843-856, 2019 May.
  37. Martínez-Cortés I, Acevedo-Domínguez NA, Olguin-Alor R, Cortés-Hernández A, Álvarez-Jiménez V, Campillo-Navarro M, Sumano-López HS, Gutiérrez-Olvera L, Martínez-Gómez D, Maravillas-Montero JL, Loor JJ, García-Zepeda EA, Soldevila G. Tilmicosin modulates the innate immune response and preserves casein production in bovine mammary alveolar cells during Staphylococcus aureus infection. Journal of Animal Science 97(2) :644-656, 2019 Feb 1.
  38. Piedra-Quintero ZL, Serrano C, Villegas-Sepúlveda N, Maravillas-Montero JL, Romero-Ramírez S, Shibayama M, Medina-Contreras O, Nava P, Santos-Argumedo L. Myosin 1F regulates M1-polarization by stimulating intercellular adhesion in macrophages. Frontiers in Immunology 9:3118. 2019 Ene 10.
  39. Meza-Sánchez DE and Maravillas-Montero JL. Clinical and biomedical applications of surface plasmon resonance systems. Revista de Investigación Clínica/Clinical and Translational Investigation 71(2):85-90, 2019
  40. Pérez-Martínez CA, Maravillas-Montero JL, Meza-Herrera I, Vences-Catalán F, Zlotnik A, Santos-Argumedo L. 2017. Tspan33 is Expressed in Transitional and Memory B Cells, but is not Responsible for High ADAM10 Expression. Scand J Immunol. Jul; 86(1):23-30
  41. Maravillas-Montero JL, Acevedo-Ochoa E. 2017. Human B Regulatory Cells: The New Players in Autoimmune Disease. Rev Invest Clin. Sep-Oct; 69(5):243-246.
  42. Melo-Nava B, Casas-González P, Pérez-Solís M, Castillo-Badillo J, Maravillas-Montero JL, Jardón-Valadez E, Zariñán T, Aguilar-Rojas A, Gallay N, Reiter E, Ulloa-Aguirre A. Role of cysteine residues in the carboxyl-terminus of the follicle-stimulating hormone receptor in intracellular traffic and postendocytic processing. Frontiers in Cell and Developmental Biology, 4:76, 2016.
  43. Lopez-Herrera G.*, Maravillas-Montero JL.*, Vargas-Hernández A., Berron-Ruiz L., Ramirez-Sanchez E., Yamazaki-Nakashimada MA., Espinosa-Rosales FJ., Santos-Argumedo L. A novel CD40LG deletion causes the hyper-IgM syndrome with normal CD40L expression in a 6-month-old child. Immunologic Research. 2015, May;62(1):89-94. *Igual contribución.

Previas

  1. Maravillas-Montero JL., Burkhardt AM., Hevezi PA., Carnevale CD., Smit MJ. and Zlotnik A. Cutting Edge: GPR35/CXCR8 is the Receptor of the Mucosal Chemokine CXCL17. The Journal of Immunology. 2015, Jan 1;194(1):29-33.
  2. Burkhardt AM.*, Maravillas-Montero JL.*, Carnevale CD., Vilches-Cisneros N., Flores JP., Hevezi PA. and Zlotnik A. CXCL17 is a major chemotactic factor for lung macrophages. The Journal of Immunology. 2014, Aug 1;193(3):1468-74. *Igual contribución.
  3. Maravillas-Montero JL., López-Ortega O., Patiño-López G. and Santos-Argumedo L. Myosin 1g regulates cytoskeleton plasticity, cell migration, exocytosis and endocytosis in B lymphocytes. European Journal of Immunology. 2014, Mar;44(3):877-86.
  4. Luu VP., Hevezi P., Vences-Catalán F., Maravillas-Montero JL., White CA., Casali P., Llorente L., Jakez-Ocampo J., Lima G., Vilches-Cisneros N., Flores-Gutiérrez JP., Santos-Argumedo L. and Zlotnik A. TSPAN33 is a novel marker of activated and malignant B cells. Clinical Immunology. 2013, Dec;149(3B):388-99.
  1. Emilia R. Gutiérrez-Mireles, José Carlos Páez-Franco, Raúl Rodríguez-Ruíz, Juan Manuel Germán-Acacio, M. Casandra López-Aquino & Manuel Gutiérrez-Aguilar (2023) An Arabidopsis mutant line lacking the mitochondrial calcium transport regulator MICU shows an altered metabolite profile, Plant Signaling & Behavior, 18:1, DOI: 10.1080/15592324.2023.2271799
  2. Villeda-Villegas, M., Páez-Franco, J. C., Coyote-Dotor, G., Núñez-Pineda, A., Dorazco-González, A., Fuentes-Noriega, I., Rubio-Carrasco, K., Jaldín, H. P. T., Morales-Morales, D., & Germán-Acacio, J. M. (2023). Diversity of solid forms promoted by ball milling: Characterization and intrinsic dissolution studies of pioglitazone hydrochloride and fluvastatin sodium Drug-Drug Systems. Pharmaceuticals, 16(6), 781. https://doi.org/10.3390/ph16060781
  3. Tecocoatzi, M. F. M., Páez-Franco, J. C., Rubio-Carrasco, K., Núñez-Pineda, A., Dorazco-González, A., Fuentes-Noriega, I., Vilchis-Néstor, A. R., Olvera, L. I., Morales-Morales, D., & Germán-Acacio, J. M. (2023). Ball-Milling Preparation of the Drug-Drug solid form of Pioglitazone-Rosuvastatin at different molar ratios: Characterization and Intrinsic dissolution Rates Evaluation. Pharmaceutics, 15(2), 630. https://doi.org/10.3390/pharmaceutics15020630
  4. Alvarez-Ricardo, Y., Meza-Morales, W., Obregón-Mendoza, M. A., Toscano, R. A., Núñez-Zarur, F., Germán-Acacio, J. M., Puentes-Díaz, N., Alí-Torres, J., Arenaza-Corona, A., Ramírez-Apán, M. T., Morales-Morales, D., & Enríquez, R. G. (2023). Synthesis, characterization, theoretical studies and antioxidant and cytotoxic evaluation of a series of Tetrahydrocurcumin (THC)-benzylated derivatives. Journal of Molecular Structure, 1273, 134355. https://doi.org/10.1016/j.molstruc.2022.134355
  5. Alvarez-Ricardo, Y., Sánchez-López, D. M., Meza-Morales, W., Obregón-Mendoza, M. A., Arenaza-Corona, A., Germán-Acacio, J. M., Toscano, R. A., Zermeño-Ortega, M. R., Morales-Morales, D., & Enríquez, R. G. (2022). Spontaneous Enantiomeric Resolution of 1,3-Diols from the Naphtylidene Derivative of 2,4-Pentanedione. Molbank, 2022(4), M1457. https://doi.org/10.3390/m1457
  6. Páez-Franco, J. C., Maravillas-Montero, J. L., Mejía-Domínguez, N. R., Torres-Ruíz, J., Tamez-Torres, K. M., Pérez-Fragoso, A., Germán-Acacio, J. M., Ponce-De-León, A., Gómez-Martín, D., & Ulloa-Aguirre, A. (2022). Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology. PLOS ONE, 17(9), e0274910. https://doi.org/10.1371/journal.pone.0274910
  7. Gómez-Benítez, V., Germán-Acacio, J. M., & Morales-Morales, D. (2022). Mechanochemistry - a promising tool on the synthesis of organometallic pincer compounds: Current state and future perspectives. Current Organic Chemistry, 26(5), 438-443. https://doi.org/10.2174/1385272826666220214110600
  8. Morales-Morales, D., Juarez-Garrido, H., Germán-Acacio, J. M., Jaime-Adán, E., Barroso-Flores, J., Lara, V., Reyes-Martínez, R., Toscano, R. A., & Ortega, S. H. (2022). Synthesis of a series of Pd(ii) complexes of the type [Pd(1,10-phen)(SRF)2]: an interesting case of solvatomorphism. CrystEngComm, 24(45), 7932–7943. https://doi.org/10.1039/d2ce01319c
  9. Páez-Franco JC, Zermeño-Ortega MR, de la O-Contreras CM, Canseco-González D, Parra-Unda JR, Ávila-Sorrosa A, Enríquez RG, Germán-Acacio JM*, Morales-Morales D*. Relevance of Fluorinated Ligands to the Design of Metallodrugs for their Potential Use in Cancer Treatment. Pharmaceutics, 2022, 14: 402.
  10. Rosales-Vázquez LD, Valdes-García J, Germán-Acacio JM, Páez-Franco JC, Martínez-Otero D, Vilchis-Nestor AR, Barroso-Flores J, Sánchez-Mendieta V, Dorazco-González A. A water-stable luminescent Zn-MOF based on a conjugated π-electron ligand as an efficient sensor for atorvastatin and its application in pharmaceutical samples. J. Mater. Chem. C. 2022, 10: 5944-5955.
  11. Morales-Espinosa EG, Ortiz-Pastrana N, Gómez-Benítez V, Reyes-Martínez R, Piñón-Castillo HA, Manjarrez-Nevárez LA, Germán-Acacio JM, Morales-Morales. Synthesis and Characterization of Two Isostructural POCOP Ni(II) Pincer Complexes Containing Fluorothiophenolate Ligands: [Ni(SC6F4-4-H){C6H2-3-(C2H3O)-2,6-(OPiPr2)2}] and [Ni(SC6F5){C6H2-3-(C2H3O)-2,6-(OPiPr2)2}]. Molbank. 2022, 2022(2): M1359.
  12. Gómez-Benítez V, Germán-Acacio JM*, Morales-Morales D*. Mechanochemistry a Promising Tool on the Synthesis of Organometallic Pincer Compounds. Current State and Future Perspectives. Curr. Org. Chem. 2022, 26(5): 438-443.
  13. Valdés H*, Germán-Acacio JM*, van Koten G*, Morales-Morales D*. Bimetallic Complexes that merge Metallocene and Pincer-Metal Building Blocks: Synthesis, Stereochemistry and Catalytic Reactivity. Dalton Trans. 2022, 51: 1724-1744. https://doi.org/10.1039/D1DT03870B.
  14. Valdes-García J, Viviano-Posadas AO, Rivera-Chávez J, Ramírez-Apan T, Martínez-Vargas S, Aguirre-Hernández E, German-Acacio JM, Morales-Morales D, Dorazco-González A. Crystal structures and study of interaction mode of bis-benzimidazole-benzene derivatives with DNA. J. Mol. Struct. 2022, 1249: 131582.
  15. Coyote-Dotor G, Páez-Franco JC, Canseco-González D, Núñez-Pineda A, Dorazco-González A, Fuentes-Noriega I, Vilchis-Néstor AR, Rodríguez-Hernández J, Morales-Morales D, Germán-Acacio JM*. Synthesis, Characterization, and Intrinsic Dissolution Studies of Drug–Drug Eutectic Solid Forms of Metformin Hydrochloride and Thiazide Diuretics. Pharmaceutics. 2021, 13: 1926.
  16. De-la-Cruz-Martínez L, Duran-Becerra C, González-Andrade M, Páez-Franco JC, Germán-Acacio JM, Espinosa-Chávez J, Torres-Valencia JM, Pérez-Villanueva J, Palacios-Espinosa JF, Soria-Arteche O, et al. Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, InVitro and In Silico Studies. Molecules. 2021, 26: 4375.
  17. Solares-Briones M, Coyote-Dotor G, Páez-Franco JC, Zermeño-Ortega MR, de la O Contreras Ca. M., Canseco-González D, Avila-Sorrosa A, Morales-Morales D,* Germán-Acacio JM*. Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals. Pharmaceutics. 2021, 13: 790.
  18. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  19. Rufino-Felipe E, Valdés H, Germán-Acacio JM, Reyes-Márquez M, Morales- Morales D. Fluorinated N-Heterocyclic carbene complexes. Applications in catalysis. J. Organomet. Chem. 2020, 921, 121364.
  20. Jaime-Adán E, Germán-Acacio JM, Toscano RA, Hernández-Ortega S, Valdés- Martínez S. Imine-Benzoic Acid Cocrystals as a Tool to Study Intermolecular Interactions in Schiff Bases. Cryst. Growth & Des. 2020, 20, 2240–2250.
  21. Luis D. Rosales-Vázquez, Josue Valdes-García, Iván J. Bazany-Rodríguez, Juan M. Germán-Acacio, Diego Martínez-Otero, Alfredo R. Vilchis-Néstor, Raúl Morales-Luckie, Víctor Sánchez-Mendieta and Alejandro Dorazco-González. A sensitive photoluminescent chemosensor for cyanide in water based on a zinc coordination polymer bearing ditert-butyl-bipyridine. Dalton Trans. Jul 10. 2019.
  22. Valente Gómez-Benítez, Hugo Valdés, Simón Hernández-Ortega, Juan Manuel German-Acacio, David Morales-Morales. SPS–Ni(II) pincer compounds of the type [Ni(phPS2)(P(C6H4-4-R)3)] Synthesis, characterization and catalytic evaluation in C-S cross-coupling reactions. Polyhedron, 143: 144-148, 2018.
  23. Plata-Vargas, E.; de la Cruz-Hernández, C.; Dorazco-González, A.; Fuentes-Noriega, I.; Morales-Morales, D. and Juan Manuel Germán-Acacio, J. Synthesis of Metforminium Succinate by Melting. Crystal Structure, Thermal, Spectroscopic and Dissolution Properties. Journal of the Mexican Chemical Society, 61(3), 197-204, 2017.
  24. Germán-Acacio, J. and David Morales-Morales, D. Combination Therapy Including Metformin hydrochloride for the Treatment of Diabetes and Related Comorbidity: A Patent Filed Survey. Organic & Medicinal Chemistry IJ., 1(4): 555569. Review Article, Volume 1 Issue 4 - March, 2017
  25. Ramos-Espinosa, A.; Valdés, H.; Ramírez-Apan, M.; Hernández-Ortega, S.; Aguilar-Castillo, B.; Reyes-Martínez, R.; Germán-Acacio, J. and Morales-Morales, D. N-(R)ethanolamine dithiocarbamate ligands and their Ni(II) and Pt(II) complexes. Evaluation of the in vitro anticancer activity of the Pt(II) derivatives. Inorganica Chimica Acta, 466, 584–590, 2017.
  26. J. R. Pioquinto-Mendoza, J. A. Rosas-Ortíz, R. Reyes-Martínez, P. Conelly-Espinosa, R. A. Toscano, J. M. Germán-Acacio, A. Ávila-Sorrosa, O. Baldovino-Pantaleón, D. Morales-Morales. Synthesis, characterization and molecular structures of Ni(II) complexes derived from Schiff base pyridylimine ligand. Inorg. Chim. Acta, 2015, 438, 146-152.
  27. J. R. Pioquinto-Mendoza, P. Conelly-Espinosa, R. Reyes-Martínez, R. A. Toscano, J. M. Germán-Acacio, A. Ávila-Sorrosa, O. Baldovino-Pantaleón, D. Morales-Morales. Synthesis, characterization and molecular structures of Ni(II) complexes derived from Schiff base pyridylimine ligand. A simple and facile to prepare Pd(II) complex containing the pyridyl imine ligand [C5H4N-2-CH3C=N-(CH2)3NH2]. Structural characterization and catalytic evaluation in Suzuki-Miyaura C-C couplings. J. Organomet. Chem., 2015, 797, 153-158.

Previas

  1. Alcives Ávila-Sorrosa, Alicia Reyes-Arellano, Juan Manuel Germán-Acacio, Reyna Reyes-Martínez and David Morales-Morales. trans-Bis(l-benzenethiolato-κ2S:S)-bis[chlorido(triphenylphosphane-κP)palladium(II)] chloroform disolvate. Acta Cryst. E., 2013, 69, m472.
  2. Evelyn Paz-Morales, Manuel Basauri-Molina, Juan Manuel Germán-Acacio, Reyna Reyes-Martínez and David Morales-Morales. 1,3-Bis[(tert-butylsulfanyl)methyl]-2,4,6-trimethylbenzene. Acta Cryst. E., 2013, 69, o306.
  3. Magdalena Quezada-Miriel, Alcives Ávila-Sorrosa, Juan Manuel Germán-Acacio, Reyna Reyes-Martínez and David Morales-Morales. 3-[1-(3-Hydroxybenzyl)-1H-benzimidazol-2-yl]phenol dimethyl sulfoxide monosolvate. Acta Cryst. E., 2012, 68, o3053-o3054.

Contribuciones en libros

  1. German-Acacio JM, Meza-Sánchez DE, Morales-Morales D. Chapter 3. Therapeutically Relevant Natural Products as AMPK Activators in the treatment of Diabetes. Atta-ur-Rahman Ed., Elsevier Science Publishers, Vol. 66, 2020, 1st Ed., The Netherlands
  2. Valdés, H.; Germán-Acacio, J. and Morales-Morales, D. Chapter 7 - Strategies for the design and synthesis of pincer-based dendrimers: Potential applications. En: Organic Materials as Smart Nanocarriers for Drug Delivery. Edited by:Alexandru Mihai Grumezescu. William Andrew, pp. 245-291, 2018.

Patentes

  1. Patente mexicana concedida. FASES SÓLIDAS EUTÉCTICAS FÁRMACO-FÁRMACO PARA EL TRATAMIENTO DE PACIENTES DIABÉTICOS HIPERTENSOS. Patente concedida (16 de febrero de 2021) MX/a/2017/013510, número de título 379944. Inventores: Juan Manuel Germán-Acacio, Cynthia Barrios Barrera, Joelis Rodríguez-Hernández, Alejandro Dorazco-González, Jesús Valdés-Martínez y David Morales-Morales.
  2. Registro ante el IMPI de la patente mexicana FASES SÓLIDAS FÁRMACO FÁRMACO CONTENIENDO TIAZOLIDINEDIONAS Y ESTATINAS. Patente en proceso de concesión (pago del título) MX/a/2018/015062.
  3. Registro ante el IMPI de la patente mexicana FASES SÓLIDAS FÁRMACO FÁRMACO CONTENIENDO METFORMINA Y ESTATINAS. Solicitud de patente MX/a/2019/003115.
  1. Velázquez-Cervantes, M., Benítez-Zeferino, Y. R., Flores-Pliego, A., Helguera-Repetto, A. C., Meza-Sánchez, D. E., Maravillas-Montero, J. L., León-Reyes, G., Mancilla-Ramírez, J., Cerna-Cortés, J. F., Baeza-Ramírez, M. I., & León-Juárez, M. (2023). A review study of the participation of late domains in sorting and transport of viral factors to exosomes. Life, 13(9), 1842. https://doi.org/10.3390/life13091842
  2. Romero-Ramírez, S., Sosa-Hernández, V. A., Cervantes-Díaz, R., Carrillo-Vázquez, D. A., Meza-Sánchez, D. E., Núñez-Álvarez, C. A., Torres-Ruíz, J., Gómez-Martín, D., & Maravillas-Montero, J. L. (2023). Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1080154
  3. Jiram Torres-Ruiz, Julieta Lomelín-Gascón, Jaquelin Lira Luna, Ana Sofia Vargas- Castro, Alfredo Pérez-Fragoso, Miroslava Nuñez-Aguirre, Beatriz Alcalá-Carmona, Abdiel Absalón-Aguilar, Jennifer T. Balderas-Miranda, José Luis Maravillas-Montero, Nancy R. Mejía-Domínguez, Carlos Núñez-Álvarez, Luis Llorente, Sandra Romero-Ramírez, Victor Andrés Sosa-Hernández, Rodrigo Cervantes-Díaz, Guillermo Juárez-Vega, David Meza-Sánchez, Marina Rull-Gabayet, Luis Alberto Martínez-Juárez, Linda Morales, Lizeth Naomi López-López, José Adrián Negrete-Trujillo, Jorge Abelardo Falcón-Lezama, Rafael Ricardo Valdez-Vázquez, Héctor Gallardo-Rincón, Roberto Tapia-Conyer & Diana Gómez-Martín (2023) Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study, Infectious Diseases, 55:4, 243-254, DOI: 10.1080/23744235.2022.2158217
  4. Torres-Ruiz J, Lomelín-Gascón J, Vargas-Castro AS, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Rull-Gabayet M, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez DE, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study. Front Immunol. 2022 Aug 15;13:943563. doi: 10.3389/fimmu.2022.943563.
  5. Sosa-Hernández Víctor A., Romero-Ramírez Sandra, Cervantes-Díaz Rodrigo, Carrillo-Vázquez Daniel A., Navarro-Hernandez Itze C., Whittall-García Laura P., Absalón-Aguilar Abdiel, Vargas-Castro Ana S., Reyes-Huerta Raúl F., Juárez-Vega Guillermo, Meza-Sánchez David E., Ortiz-Navarrete Vianney, Torres-Ruiz Jiram, Mejía-Domínguez N.R., Gómez-Martín Diana, Maravillas-Montero José L. (2022) CD11c+ T-bet+ CD21hi B Cells Are Negatively Associated With Renal Impairment in Systemic Lupus Erythematosus and Act as a Marker for Nephritis Remission. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.892241
  6. Cervantes-Díaz R, Sosa-Hernández VA, Romero-Ramírez S, Torres-Ruiz J, Pérez-Fragoso A, Meza-Sánchez DE, Gómez-Martín D, Maravillas-Montero JL. Circulating B10 regulatory cells are decreased in severe and critical COVID-19. J Leukoc Biol. 2022 Aug;112(2):333-337. doi: 10.1002/JLB.5COVCRA0721-387RR.
  7. Cervantes-Díaz R, Sosa-Hernández VA, Torres-Ruíz J, Romero-Ramírez S, Cañez-Hernández M, Pérez-Fragoso A, Páez-Franco JC, Meza-Sánchez DE, Pescador-Rojas M, Sosa-Hernández VA, Gómez-Martín D, Maravillas-Montero JL. Severity of SARS-CoV-2 infection is linked to double-negative (CD27- IgD-) B cell subset numbers. Inflamm Res. 2022 Jan;71(1):131-140. doi: 10.1007/s00011-021-01525-3. Epub 2021 Nov 30.
  8. Torres-Ruiz J, Lomelín-Gascón J, Lira-Luna J, Pérez-Fragoso A, Tapia-Conyer R, Nuñez-Aguirre M, Alcalá-Carmona B, Absalón-Aguilar A, Maravillas-Montero JL, Mejía-Domínguez NR, Núñez-Álvarez C, Llorente L, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Juárez-Vega G, Meza-Sánchez D, Rull-Gabayet M, Martínez-Juárez LA, Morales-Juárez L, López-López LN, Negrete-Trujillo JA, Falcón-Lezama JA, Valdez-Vázquez RR, Gallardo-Rincón H, Gómez-Martín D. FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients. Clin Transl Med. 2021 Nov;11(11):e623.
  9. Torres-Ruiz J, Absalón-Aguilar A, Nuñez-Aguirre M, Pérez-Fragoso A, Carrillo-Vázquez DA, Maravillas-Montero JL, Mejía-Domínguez NR, Llorente L, Alcalá-Carmona B, Lira-Luna J, Núñez-Álvarez C, Juárez-Vega G, Meza-Sánchez D, Hernández-Gilsoul T, Tapia-Rodríguez M, Gómez-Martín D. Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity. Cells. 2021 Sep 26;10(10):2545.
  10. Torres-Ruiz J, Pérez-Fragoso A, Maravillas-Montero JL, Llorente L, Mejía-Domínguez NR, Páez-Franco JC, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Absalón-Aguilar A, Nuñez-Aguirre M, Juárez-Vega G, Meza-Sánchez D, Kleinberg-Bid A, Hernández-Gilsoul T, Ponce-de-León A, Gómez-Martín D. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021 Sep 8;12:689966.
  11. Navarro-Hernandez IC, Acevedo-Ochoa E, Juárez-Vega G, Meza-Sánchez DE, Hernández-Hernández JM, Maravillas-Montero JL. Size Determination and Phenotypic Analysis of Urinary Extracellular Vesicles using Flow Cytometry. J Vis Exp. 2021 Apr 23;(170). doi: 10.3791/61695.
  12. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  13. Cervantes-Díaz R, Sosa-Hernández VA, Torres-Ruíz J, Romero-Ramírez S, Cañez-Hernández M, Pérez-Fragoso A, Páez-Franco JC, Meza-Sánchez DE, Pescador-Rojas M, Sosa-Hernández VA, Gómez-Martín D, Maravillas-Montero JL. Severity of SARS-CoV-2 infection is linked to double-negative (CD27- IgD-) B cell subset numbers. Inflamm Res. 2022 Jan;71(1):131-140. doi: 10.1007/s00011-021-01525-3. Epub 2021 Nov 30.
  14. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.
  15. Navarro-Hernandez IC, López-Ortega O, Acevedo-Ochoa E, Cervantes-Díaz R, Romero-Ramírez S, Sosa-Hernandez VA, Meza-Sánchez DE, Juárez-Vega G, Pérez-Martínez CA, Chávez-Munguía B, Galván-Hernández A, Antillón A, Ortega- Blake I, Santos-Argumedo L, Hernández-Hernández JM, Maravillas-Montero JL.Tetraspanin 33 (TSPAN33) Regulates Endocytosis and Migration of Human B Lymphocytes by Affecting the Tension of the Plasma Membrane. The FEBS Journal. 2020,287(16):3449-3471.
  16. Romero-Ramírez S, Navarro-Hernandez IC, Cervantes-Díaz R, Sosa-Hernández VA, Acevedo-Ochoa E, Kleinberg-Bild A, Valle-Rios R, Meza-Sánchez DE, Hernández-Hernández JM, Maravillas-Montero JL. Innate-like B cell subsets during immune responses: Beyond antibody production. Journal of Leukocyte Biology 105(5):843-856, 2019 May.
  17. Meza-Sánchez DE and Maravillas-Montero JL. Clinical and biomedical applications of surface plasmon resonance systems. Revista de Investigación Clínica/Clinical and Translational Investigation 71(2):85-90, 2019.
  18. Shrivastava G, León-Juárez M, García-Cordero J, Meza-Sánchez DE, Cedillo-Barrón L. Inflammasomes and its importance in viral infections. Immunol Res. 2016 Dec;64(5-6):1101-1117. Review.
  19. David E. Meza Sánchez, Dimelza Suarez Pérez, Porfirio Nava Dominguez, Leticia Cedillo Barrón. Innate immune responses ex vivo skin explants infected with dengue virus. Frontiers in immu nology 2015 (Abstract)

Contribuciones en libros

  1. German-Acacio JM, Meza-Sánchez DE, Morales-Morales D. Chapter 3. Therapeutically Relevant Natural Products as AMPK Activators in the treatment of Diabetes. Atta-ur-Rahman Ed., Elsevier Science Publishers, Vol. 66, 2020, 1st Ed., The Netherlands
  1. Emilia R. Gutiérrez-Mireles, José Carlos Páez-Franco, Raúl Rodríguez-Ruíz, Juan Manuel Germán-Acacio, M. Casandra López-Aquino & Manuel Gutiérrez-Aguilar (2023) An Arabidopsis mutant line lacking the mitochondrial calcium transport regulator MICU shows an altered metabolite profile, Plant Signaling & Behavior, 18:1, DOI: 10.1080/15592324.2023.2271799
  2. Villeda-Villegas, M., Páez-Franco, J. C., Coyote-Dotor, G., Núñez-Pineda, A., Dorazco-González, A., Fuentes-Noriega, I., Rubio-Carrasco, K., Jaldín, H. P. T., Morales-Morales, D., & Germán-Acacio, J. M. (2023). Diversity of solid forms promoted by ball milling: Characterization and intrinsic dissolution studies of pioglitazone hydrochloride and fluvastatin sodium Drug-Drug Systems. Pharmaceuticals, 16(6), 781. https://doi.org/10.3390/ph16060781
  3. Tecocoatzi, M. F. M., Páez-Franco, J. C., Rubio-Carrasco, K., Núñez-Pineda, A., Dorazco-González, A., Fuentes-Noriega, I., Vilchis-Néstor, A. R., Olvera, L. I., Morales-Morales, D., & Germán-Acacio, J. M. (2023). Ball-Milling Preparation of the Drug-Drug solid form of Pioglitazone-Rosuvastatin at different molar ratios: Characterization and Intrinsic dissolution Rates Evaluation. Pharmaceutics, 15(2), 630. https://doi.org/10.3390/pharmaceutics15020630
  4. Páez-Franco, J. C., Maravillas-Montero, J. L., Mejía-Domínguez, N. R., Torres-Ruíz, J., Tamez-Torres, K. M., Pérez-Fragoso, A., Germán-Acacio, J. M., Ponce-De-León, A., Gómez-Martín, D., & Ulloa-Aguirre, A. (2022). Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology. PLOS ONE, 17(9), e0274910. https://doi.org/10.1371/journal.pone.0274910
  5. Páez-Franco JC, Zermeño-Ortega MR, de la O-Contreras CM, Canseco-González D, Parra-Unda JR, Ávila-Sorrosa A, Enríquez RG, Germán-Acacio JM*, Morales-Morales D*. Relevance of Fluorinated Ligands to the Design of Metallodrugs for their Potential Use in Cancer Treatment. Pharmaceutics, 2022, 14: 402.
  6. Rosales-Vázquez LD, Valdes-García J, Germán-Acacio JM, Páez-Franco JC, Martínez-Otero D, Vilchis-Nestor AR, Barroso-Flores J, Sánchez-Mendieta V, Dorazco-González A. A water-stable luminescent Zn-MOF based on a conjugated π-electron ligand as an efficient sensor for atorvastatin and its application in pharmaceutical samples. J. Mater. Chem. C. 2022, 10: 5944-5955.
  7. Coyote-Dotor G, Páez-Franco JC, Canseco-González D, Núñez-Pineda A, Dorazco-González A, Fuentes-Noriega I, Vilchis-Néstor AR, Rodríguez-Hernández J, Morales-Morales D, Germán-Acacio JM*. Synthesis, Characterization, and Intrinsic Dissolution Studies of Drug–Drug Eutectic Solid Forms of Metformin Hydrochloride and Thiazide Diuretics. Pharmaceutics. 2021, 13: 1926.
  8. De-la-Cruz-Martínez L, Duran-Becerra C, González-Andrade M, Páez-Franco JC, Germán-Acacio JM, Espinosa-Chávez J, Torres-Valencia JM, Pérez-Villanueva J, Palacios-Espinosa JF, Soria-Arteche O, et al. Indole- and Pyrazole-Glycyrrhetinic Acid Derivatives as PTP1B Inhibitors: Synthesis, InVitro and In Silico Studies. Molecules. 2021, 26: 4375.
  9. Solares-Briones M, Coyote-Dotor G, Páez-Franco JC, Zermeño-Ortega MR, de la O Contreras Ca. M., Canseco-González D, Avila-Sorrosa A, Morales-Morales D,* Germán-Acacio JM*. Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals. Pharmaceutics. 2021, 13: 790.
  10. José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín & Luis Llorente. Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients. Scientific Reports volume 11, Article number: 6350 (2021).
  11. Sosa-Hernández VA, Torres-Ruíz JJ, Cervantes-Díaz R, Romero-Ramírez S, Páez-Franco JC, Meza-Sánchez DE, Juárez-Vega G, Pérez-Fragoso A, Ortíz- Navarrete V, Ponce-de-León A, Llorente L, Berrón-Ruíz L, Mejía-Domínguez NR, Gómez-Martín D and Maravillas-Montero JL. B cell subsets as severity-associated signatures in COVID-19 patients. Frontiers in Immunology. 2020, 11:611004.

º Otras publicaciones

  1. Torres-Ruiz J, Pérez-Fragoso A, Maravillas-Montero JL, Llorente L, Mejía-Domínguez NR, Páez-Franco JC, Romero-Ramírez S, Sosa-Hernández VA, Cervantes-Díaz R, Absalón-Aguilar A, Nuñez-Aguirre M, Juárez-Vega G, Meza-Sánchez D, Kleinberg-Bid A, Hernández-Gilsoul T, Ponce-de-León A, Gómez-Martín D. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021 Sep 8;12:689966. eCollection (2021).
  2. Romero-Ramírez S, Navarro-Hernandez IC, Cervantes-Díaz R, Sosa-Hernández VA, Acevedo-Ochoa E, Kleinberg-Bild A, Valle-Rios R, Meza-Sánchez DE, Hernández-Hernández JM, Maravillas-Montero JL. Innate-like B cell subsets during immune responses: Beyond antibody production. Journal of Leukocyte Biology 105(5):843-856, (2019) May.
  1. Zariñán T, Mayorga J, Jardón-Valadez E, Gutiérrez-Sagal R, Maravillas-Montero JL, Mejía-Domínguez NR, Martínez-Luis I, Yacini-Torres OG, Cravioto MD, Reiter E, Ulloa-Aguirre A. A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure. J Clin Endocrinol Metab. (2021) 106(2):e534-e550.
  2. Melo-Nava B, Casas-González P, Pérez-Solís M, Castillo-Badillo J, Maravillas-Montero JL, Jardón-Valadez E, Zariñán T, Aguilar-Rojas A, Gallay N, Reiter E, Ulloa-Aguirre A. Role of cysteine residues in the carboxyl-terminus of the follicle-stimulating hormone receptor in intracellular traffic and postendocytic processing. Frontiers in Cell and Developmental Biology, 4:76, (2016).
  3. Jardón-Valadez HE. (2015) Dynamics of Membrane Proteins and Lipid Bilayers. En: Physical Biology of Proteins and Peptides. Theory, Experiment, and Simulation. L Olivares-Quiroz, O Guzmán-López, HE Jardón-Valadez (Eds), Springer International Publishing. pp 153-159.
  4. Jardón-Valadez E, Bond PJ, Ulmschneider MB. (2015) Ab initio folding of glycophorin A and acetylcholine M2 transmembrane segments via simplified environment molecular simulations. En: Physical Biology of Proteins and Peptides. Theory, Experiment, and Simulation. L Olivares-Quiroz, O Guzmán-López, HE Jardón-Valadez (Eds), Springer International Publishing. pp 115-139.
  1. Aguilar-Valdés A., Noriega L-G., Tovar A.R., Ibarra-Sánchez M.J., Sosa-Hernández V.A., Maravillas-Montero J.L., Martínez-Aguilar J. SWATH-MS proteomics of PANC-1 and MIA PaCa-2 pancreatic cancer cells allows identification of drug targets alternative to MEK and PI3K inhibition, Biochem Biophys Res Commun, 552 (2021) 23-29.
  2. Navarrete-Bernal MGC, Cervantes-Badillo MG, Martínez-Herrera JF, Lara-Torres CO, Gerson-Cwilich R, Zentella-Dehesa A, Ibarra-Sánchez MJ, Esparza-López J, Montesinos JJ, Córtes-Morales VA, Osorio-Pérez D, Villegas-Osorno DA, Reyes- Sánchez E, Salazar-Sojo P, Tallabs-Utrilla LF, Romero-Córdaba S, Rocha-Zavaleta L. Biological landscape of triple negative breast cancer expressing ctl-4. Front Oncol. 2020, 10:1206
  3. Esparza-López J, Alvarado-Muñoz JF, Escobar-Arriaga E, Ulloa-Aguirre A, Ibarra-Sánchez MJ. Metformin reverses mesenchymal phenotype of primary breaset cancer cells through STAT3/NF-kB pathways. BMC Cancer, 19:728, 2019.
  4. Alvarado-Muñoz, J.F., Esparza-López, J., Escobar-Arriaga, E., De la Cruz-Escobar, E.N., León-Rodríguez, E., Ibarra-Sánchez, M.J. La interleucina 6 induce transición epitelio-mesénquima en células de cáncer de mama. Gaceta Mexicana de Oncología 16(2):113-117, 2017.
  1. Aguilar-Valdés A., Noriega L-G., Tovar A.R., Ibarra-Sánchez M.J., Sosa-Hernández V.A., Maravillas-Montero J.L., Martínez-Aguilar J. SWATH-MS proteomics of PANC-1 and MIA PaCa-2 pancreatic cancer cells allows identification of drug targets alternative to MEK and PI3K inhibition, Biochem Biophys Res Commun, 552 (2021) 23-29.
  2. Esparza-López, J., Martínez-Aguilar J., Ibarra-Sánchez M.J. Deriving primary cancer cell cultures for personalized therapy. Rev Invest Clin, 71 (2019) 369-380.

Contribuciones en libros

  1. Martínez-Aguilar J., Molloy M.P. (2019). Targeted Mass Spectrometry of S100 Proteins. En: Heizmann C. (eds) Calcium-Binding Proteins of the EF-Hand Superfamily. Methods in Molecular Biology, vol 1929. Humana Press, New York, NY.

Previas

  1. Martínez-Aguilar, J.; Clifton-Bligh, R.; Molloy, M. P., Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Scientific Reports, 6 (2016) 1-12
  2. Martínez-Aguilar, J.; Clifton-Bligh, R.; Molloy, M. P., A multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours. BMC Cancer. 2015, 15:199
  3. Martínez-Aguilar, J.; Molloy, M. P., Label-free selected reaction monitoring enables multiplexed quantitation of S100 protein isoforms in cancer cells. J Proteome Res. 2013, 12, (8) 3679-88
  4. Martínez-Aguilar, J.; Chik, J.; Nicholson, J.; Semaan, C.; McKay, M. J.; Molloy, M. P., Quantitative mass spectrometry for colorectal cancer proteomics. Proteomics-clinical applications 2013, 7, (1-2), 42-54.
  1. Contreras-Espinosa L, Alcaraz N, De La Rosa-Velázquez IA, Díaz-Chávez J, Cabrera-Galeana P, Rebollar-Vega R, Reynoso-Noveron N, Maldonado-Martínez HA, González-Barrios R, Montiel-Manríquez R, Bautista-Sánchez D, Castro-Hernández C, Álvarez-Gómez RM, Jiménez-Trejo F, Tapia-Rodríguez M, García-Gordillo J, Pérez-Rosas A, Bargallo-Rocha E, Arriaga-Canon C, Herrera LA. Transcriptome Analysis Identifies GATA3-AS1 as a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients. J Mol Diagn. 2021 Aug
  2. Zyanya Lucia Zatarain Barrón, Brenda Marquina-Castillo, Jorge Alberto Barrios-Payan, Fernanda Cornejo, Otoniel Maya-Lucas, Gamaliel López-Leal, Camilo Molina, Richard M Anthony, Adrián Ochoa-Leyva, Inti Alberto de la Rosa, Rosa Gloria Rebollar-Vega, Robin Mark Warren, Rogelio Hernández Pando, Dulce Adriana Mata, Dick van Soolingen. Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis. Front. Immunol., 19 May 2020
  3. Rebollar-Vega RG, Arriaga-Canon C and de la Rosa-Velázquez IA. Clinical Applications of Next-Generation Sequencing. Rev Invest Clin. 2018; 70(4):153-157.
  4. Arriaga-Canon C, De La Rosa-Velázquez IA, González-Barrios R, Montiel-Manríquez R, Oliva-Rico D, Jiménez-Trejo F, Cortés-González C, and Herrera LA. The use of long non-coding RNAs as prognostic biomarkers and therapeutic targets in prostate cancer. Oncotarget. April 17, 2018; 9:20872-20890.
  5. Guerra-Calderas, L., González-Barrios, R., Patiño, C.C., Alcaraz, N., Salgado-Albarrán, M., de León, D.C., Hernández, C.C., Sánchez-Pérez, Y., Maldonado-Martínez, H.A., De la Rosa-Velazquez, I.A., Vargas-Romero, F., Herrera, L.A., García-Carrancá, A., Soto-Reyes, E. CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines. Oncotarget Vol 9, Issue 24, 30 March 2018, Pages 17028-17042

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